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2025 ICD-10-CM code C7A

Malignant neuroendocrine tumors (NETs). Code also any associated multiple endocrine neoplasia (MEN) syndromes (E31.2-). Use additional code to identify any associated endocrine syndrome, such as carcinoid syndrome (E34.0).

Refer to the ICD-10-CM Official Guidelines for Coding and Reporting for specific instructions on coding malignant neuroendocrine tumors, including the use of additional codes for associated syndromes and manifestations.

Medical necessity for treatment of malignant neuroendocrine tumors is established by the confirmed diagnosis through biopsy and imaging, and the presence of symptoms or potential for complications related to hormone overproduction and tumor growth.

Clinicians should evaluate patients for signs and symptoms related to hormone overproduction and organ dysfunction depending on the tumor location. Diagnosis involves physical examination, laboratory tests (blood and urine hormone levels), imaging studies (CT, MRI, PET), and biopsy for histopathological and molecular analysis.

In simple words: Malignant neuroendocrine tumors (NETs) are a type of cancer made up of cells that act like both nerve and hormone-producing cells.These tumors can release too many hormones, causing problems in different parts of the body like the digestive system, lungs, and pancreas.Symptoms depend on where the tumor is located, but can include flushing, diarrhea, and breathing problems.

Malignant neuroendocrine tumors (NETs) are neoplasms composed of cells that possess characteristics of both nerve and endocrine cells. These tumors can secrete excessive amounts of hormones and hormone-like substances, leading to various systemic effects.NETs can occur in various locations throughout the body, including the digestive system, lungs, pancreas, liver, kidneys, and reproductive system.It is important to also code for any associated multiple endocrine neoplasia (MEN) syndromes (E31.2-) and any associated endocrine syndrome, such as carcinoid syndrome (E34.0). Excludes2: malignant pancreatic islet cell tumors (C25.4) and Merkel cell carcinoma (C4A.-).

Example 1: A patient presents with flushing, diarrhea, and wheezing. After a thorough examination, including imaging and biopsy, a diagnosis of malignant neuroendocrine tumor of the small intestine with associated carcinoid syndrome is confirmed.The codes C7A and E34.0 are assigned., A patient with a history of multiple endocrine neoplasia type 1 (MEN1) is found to have a malignant neuroendocrine tumor of the pancreas. The codes C7A and E31.2 are assigned., A patient undergoes a CT scan which reveals a malignant neuroendocrine tumor in the lung. Biopsy confirms the diagnosis, and no associated syndromes are identified. The code C7A is assigned.

Documentation should include details of the tumor's location, size, and characteristics.Histopathology reports from biopsies are crucial for confirmation.Evidence of hormone overproduction and related symptoms should be documented, along with any associated syndromes like MEN or carcinoid syndrome.

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