2025 ICD-10-CM code C86
(Active) Effective Date: N/A Malignant neoplasms of lymphoid, hematopoietic and related tissue - T/NK-cell lymphoma Chapter 2: Neoplasms (C00-D49) Feed
Other specified types of T/NK-cell lymphoma. This code represents a rare and aggressive type of non-Hodgkin lymphoma involving abnormal NK cells, a type of T-cell lymphocyte.
Medical necessity is established by the confirmed diagnosis of T/NK-cell lymphoma through biopsy and appropriate diagnostic testing. The chosen treatment approach must be consistent with established guidelines for this type of lymphoma.
The provider diagnoses the condition based on history, signs and symptoms, and physical examination. Diagnostic procedures include lymph node biopsy and microscopic analysis of the specimen, complete blood cell (CBC) count, LDH, kidney function tests, liver function tests, and antibody tests for EBV. Imaging studies include CT or PET to determine the extent of malignancy and stage the disease. Treatment depends on the stage and severity of the disease and may include chemotherapy, radiation, or a combination of both.
- Chapter 2: Neoplasms (C00-D49)
- C81-C96: Malignant neoplasms of lymphoid, hematopoietic and related tissue
In simple words: This refers to a rare, fast-growing cancer of the immune system. It happens when natural killer (NK) cells, a type of white blood cell, become cancerous and multiply uncontrollably. This particular code is used when the specific type of T/NK-cell lymphoma isn't covered by any other code.
Other specified types of T/NK-cell lymphoma refer to an aggressive type of non-Hodgkin lymphoma (NHL) that occurs when natural killer (NK) cells, a type of T cell lymphocytes, become abnormal and multiply. The provider identifies a type of T/NK cell lymphoma not represented by another code.It is characterized by vascular damage and destruction, prominent necrosis, cytotoxic phenotype, and association with Epstein-Barr virus (EBV).
Example 1: A patient presents with painless tumors in the neck, enlarged lymph nodes, fever, and night sweats.A biopsy confirms T/NK-cell lymphoma, and imaging reveals localized disease. The patient is treated with chemotherapy and radiation., A patient experiences persistent fatigue, weight loss, and bone pain.Blood tests and imaging reveal widespread T/NK-cell lymphoma with lymph node and bone marrow involvement. The patient receives systemic chemotherapy and is considered for a stem cell transplant., A patient presents with nasal obstruction and bleeding. A biopsy reveals extranodal NK/T-cell lymphoma, nasal type. The patient is treated with combined chemotherapy and radiotherapy.
Documentation should include biopsy results, immunophenotyping, imaging reports (CT, PET), blood test results (CBC, LDH, kidney and liver function tests, EBV antibody tests), and details of the treatment plan.
** Excludes1: anaplastic large cell lymphoma, ALK negative (C84.7-) anaplastic large cell lymphoma, ALK positive (C84.6-) mature T/NK-cell lymphomas (C84.-) other specified types of non-Hodgkin lymphoma (C85.8-)
- Specialties:Hematology, Oncology, Pathology
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office, Independent Clinic