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2025 ICD-10-CM code C90.21

Extramedullary plasmacytoma in remission. This refers to a plasma cell cancer outside the bone marrow that is currently showing no signs or symptoms.

Code C90.21 should be used only when the extramedullary plasmacytoma is in remission.If the patient is in relapse or has not achieved remission, different codes within the C90 category apply.

Medical necessity for services related to C90.21 should be supported by documentation of the patient's active treatment or ongoing surveillance during remission, including monitoring for recurrence, managing treatment side effects, and providing supportive care.

Diagnosis of extramedullary plasmacytoma involves a combination of physical examination, imaging studies (CT, MRI), and laboratory tests (biopsy, complete blood count, erythrocyte sedimentation rate, protein electrophoresis). Treatment options include surgical removal, radiation therapy, and chemotherapy, with regular follow-up care crucial for monitoring.

In simple words: Extramedullary plasmacytoma is a type of cancer affecting plasma cells, which are part of your immune system.This cancer forms a tumor outside of the bone marrow. "In remission" means that currently, there are no signs or symptoms of the cancer, though it may not be completely gone.

Extramedullary plasmacytoma is a type of plasma cell cancer that occurs outside the bone marrow.Plasma cells are white blood cells that produce antibodies to fight infection. In plasmacytoma, these cells become cancerous and form a tumor. "In remission" signifies that the patient currently has no signs or symptoms of the disease, although the disease itself may not be eradicated.

Example 1: A patient presents with a nasal mass, bleeding, and difficulty breathing. Biopsy reveals extramedullary plasmacytoma. After treatment, the symptoms resolve and the patient is considered to be in remission, coded as C90.21., A patient with a history of extramedullary plasmacytoma of the gastrointestinal tract achieves remission after chemotherapy and is coded as C90.21 during a follow-up visit., A patient undergoes surgical resection for an extramedullary plasmacytoma in the lung. Post-surgery, there is no evidence of disease, and the patient is coded as C90.21.

Documentation should include details of the original diagnosis, location of the tumor, treatment received, and confirmation of remission status based on clinical and laboratory findings. Imaging reports, biopsy results, and treatment summaries are essential.

** Extramedullary plasmacytoma is rare, accounting for a small percentage of plasma cell neoplasms. The presence of "in remission" is a key element of this code and reflects the patient's current disease status.

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