BETA v.3.0

2025 ICD-10-CM code C91.0

Acute lymphoblastic leukemia (ALL).

Use codes in subcategory C91.0- only for T-cell and B-cell precursor leukemia.Do not use this code for personal history of leukemia (Z85.6).

Medical necessity for treatment of ALL is established by the confirmed diagnosis based on bone marrow biopsy and/or other appropriate tests, along with the presence of symptoms or complications related to the disease.

Diagnosis and treatment of ALL typically falls under the purview of hematologists and oncologists.They are responsible for interpreting diagnostic tests, determining the appropriate treatment plan, and monitoring the patient's response to therapy.

In simple words: Acute lymphoblastic leukemia (ALL) is a type of blood cancer where the body makes too many abnormal white blood cells called lymphoblasts. These abnormal cells crowd out the healthy blood cells, making it hard for the body to fight infections and do other important jobs.

Acute lymphoblastic leukemia (ALL) is a type of cancer that affects the blood and bone marrow.It is characterized by the rapid production of abnormal, immature white blood cells called lymphoblasts. These lymphoblasts crowd out healthy blood cells in the bone marrow, leading to various symptoms.

Example 1: A 5-year-old child presents with fatigue, pallor, and recurrent infections. Blood tests reveal a high white blood cell count with a predominance of lymphoblasts. A bone marrow biopsy confirms the diagnosis of ALL., A 70-year-old adult experiences unexplained weight loss, bone pain, and easy bruising.Blood tests show abnormalities, and a bone marrow biopsy reveals ALL., A young adult with ALL undergoes chemotherapy and achieves remission. Regular follow-up appointments and blood tests are necessary to monitor for potential relapse.

Complete blood count (CBC) with differential, bone marrow aspiration and biopsy results, cytogenetic studies, molecular genetic testing, imaging studies (e.g., chest X-ray, CT scan), and documentation of any related symptoms or complications.

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