2025 ICD-10-CM code C91.9
(Active) Effective Date: N/A Malignant neoplasms of lymphoid, hematopoietic and related tissue - C91.9 2: Neoplasms (C00-D49) Feed
Lymphoid leukemia, unspecified.
Medical necessity for treatment is based on the patient's symptoms, the stage of the leukemia, and the rate of disease progression. Asymptomatic cases may be monitored with "watchful waiting," while symptomatic or rapidly progressing disease typically requires intervention such as chemotherapy, targeted therapy, or radiation.
The provider diagnoses the condition based on history, signs and symptoms, and physical examination. Diagnostic procedures include bone marrow aspiration or biopsy and microscopic analysis of the specimen, complete blood cell (CBC) count, and peripheral blood smear. Treatment depends on the stage and severity of the disease. Patients with few or no symptoms may not receive treatment, but patients who develop symptoms or show signs of progressive disease may be treated with radiation for localized disease or chemotherapy for more advanced disease.
- 2: Neoplasms (C00-D49)
- Malignant neoplasms (C00-C96)Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue (C00-C75)Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
In simple words: Lymphoid leukemia is a type of blood cancer where the body produces too many abnormal lymphocytes, a type of white blood cell.This specific code is used when the exact type of lymphoid leukemia isn't known.
Lymphoid leukemia refers to a type of cancer that leads to an increased production of lymphocytes (a type of white blood cell), which become abnormal, multiply, and collect in the peripheral blood. The provider does not document the specific type of lymphoid leukemia.
Example 1: A 65-year-old patient presents with painless swelling of lymph nodes in the neck and fatigue.Blood tests reveal abnormal lymphocytes, and a bone marrow biopsy confirms lymphoid leukemia, but the specific type is not identified. C91.9 is used., A 40-year-old patient is found to have an elevated white blood cell count during a routine physical. Further testing, including a bone marrow biopsy, leads to a diagnosis of lymphoid leukemia.The specific subtype is undetermined. C91.9 is used., A patient with a history of lymphoma experiences recurrent fevers, night sweats, and weight loss.A bone marrow biopsy suggests transformation to lymphoid leukemia, but further immunophenotyping is needed to classify the specific type.C91.9 is coded initially.
Medical documentation should include details of the diagnostic workup (physical exam, blood tests including CBC, bone marrow biopsy results, etc.) that support the diagnosis of lymphoid leukemia. Any signs or symptoms such as swollen lymph nodes, fatigue, fever, weight loss, etc. should be documented.If specific tests identifying the subtype of lymphoid leukemia are pending, this should also be noted.
** Excludes1: personal history of leukemia (Z85.6)Excludes2: Kaposi's sarcoma of lymph nodes (C46.3), secondary and unspecified neoplasm of lymph nodes (C77.-), secondary neoplasm of bone marrow (C79.52), secondary neoplasm of spleen (C78.89).
- Specialties:Hematology, Oncology
- Place of Service:Inpatient Hospital, On Campus-Outpatient Hospital, Office, Independent Clinic, Federally Qualified Health Center