2025 ICD-10-CM code C92.0
Acute myeloblastic leukemia (AML) is a type of cancer that starts in the bone marrow and quickly progresses, affecting the blood.
AML is a life-threatening malignancy requiring prompt and aggressive treatment. Medical necessity for diagnostic testing and treatment is established by the patient's clinical presentation, blood tests, bone marrow findings, and cytogenetic/molecular results.
Diagnosis involves physical exam, blood tests (CBC, peripheral smear, blood chemistries, coagulation studies), bone marrow biopsy or aspirate, lumbar puncture for CSF analysis, microscopic and cytologic examination, flow cytometry, PCR, FISH, genetic analysis, immunohistochemistry, and imaging (CT, MRI, PET, ultrasound). Treatment includes chemotherapy, targeted therapy, stem cell transplant, radiation therapy, or surgery, depending on the subtype and stage determined by FAB or WHO classifications.
In simple words: Acute myeloblastic leukemia (AML) is a cancer of the blood and bone marrow. It occurs when the body produces too many immature white blood cells, which don't function properly and crowd out healthy blood cells.
Acute myeloblastic leukemia (AML) is characterized by the rapid proliferation of abnormal myeloblasts (immature white blood cells) in the bone marrow. These abnormal cells crowd out healthy blood cells, leading to various symptoms.It includes subtypes like AML with minimal differentiation (M0), AML without maturation (M1), AML with maturation (M2), AML with t(8;21), and other specified or unspecified variants.
Example 1: A 65-year-old male presents with fatigue, frequent infections, and easy bruising. Blood tests reveal abnormal blood cell counts and a bone marrow biopsy confirms the diagnosis of AML with maturation (M2)., A 30-year-old female experiences persistent fever, bone pain, and shortness of breath. Diagnostic workup reveals acute myeloblastic leukemia with t(8;21)., A child presents with recurrent infections, pallor, and bleeding gums.A bone marrow biopsy leads to a diagnosis of acute myeloblastic leukemia, prompting immediate treatment.
Complete blood count (CBC) with differential, bone marrow biopsy or aspirate report, cytogenetic analysis, molecular testing, imaging reports (if applicable), and any other relevant clinical findings.
- Payment Status: Active
- Specialties:Hematology, Oncology
- Place of Service:Inpatient Hospital, On Campus-Outpatient Hospital, Office