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2025 ICD-10-CM code D38.4

Neoplasm of uncertain behavior of the thymus.

Code assignment should be delayed until definitive pathological results are available.If uncertain, consult with a pathologist.Using an unspecified code is not recommended.

Medical necessity is established by the presence of a thymic mass or symptoms suggestive of a thymic neoplasm.Further investigation is medically necessary to determine the nature of the lesion (benign or malignant) and guide appropriate treatment.

Diagnosis involves patient history, physical exam, imaging (chest X-ray, CT, MRI, PET scan), and biopsy.Treatment may include observation, surgery (thymusectomy), radiation therapy, or chemotherapy depending on further classification of the tumor.

IMPORTANT:Excludes1: neoplasm of uncertain behavior of heart (D48.7)

In simple words: This code indicates a tumor in the thymus gland (located in the chest) that doctors can't yet confirm as cancerous or non-cancerous based on a tissue sample. More tests are needed to know for sure.

D38.4, Neoplasm of uncertain behavior of the thymus, is an ICD-10-CM code representing a tumor of the thymus gland where histological examination cannot definitively classify it as benign or malignant.The thymus is located in the chest and plays a vital role in the immune system.This diagnosis requires further investigation to determine the nature of the neoplasm.

Example 1: A 45-year-old presents with a mediastinal mass detected on a routine chest X-ray. Biopsy reveals a thymic neoplasm, but the histology is inconclusive regarding its benign or malignant nature.Code D38.4 is assigned pending further investigation., A 60-year-old experiences chest pain and shortness of breath. Imaging shows a thymic mass.A needle biopsy is performed, but the pathology report is unable to determine whether the growth is benign or malignant.D38.4 is used., A 30-year-old patient undergoes a thymectomy for suspected thymoma.Post-operative pathology reveals features suggestive of a neoplasm, but the definitive classification (benign or malignant) remains uncertain.Code D38.4 is applied.

Patient history, physical examination findings, imaging reports (chest X-ray, CT scan, MRI, PET scan), pathology report with histological details, and any further investigations (e.g., immunohistochemistry).

** Close monitoring is crucial for patients with D38.4 until a definitive diagnosis is obtained.Further tests may include immunohistochemical staining and genetic analysis.

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