2025 ICD-10-CM code D45
Polycythemia vera
The medical necessity for treatment of polycythemia vera is based on the potential for serious complications like blood clots, heart attack, and stroke.Treatment aims to reduce the risk of these complications by controlling blood cell production and blood viscosity.
Diagnosis involves physical examination, blood tests (CBC, coagulation studies, oxygen saturation, vitamin B12, uric acid, erythropoietin levels), bone marrow aspiration/biopsy, and genetic testing for JAK2 mutation. Treatment includes phlebotomy, low-dose aspirin, medications to reduce red blood cell production, and potentially splenectomy.
In simple words: Polycythemia vera is a rare blood disease where your bone marrow makes too many blood cells, especially red ones. This makes your blood thicker and more likely to clot, which can lead to heart attack or stroke.
Polycythemia vera is a rare blood disorder characterized by uncontrolled production of blood cells, primarily red blood cells, leading to thickened blood and potential blood clots. This can cause serious complications such as heart attack or stroke.It's often discovered incidentally through routine blood tests.
Example 1: A 65-year-old patient presents with headaches, dizziness, and itching. Blood tests reveal elevated red blood cell count and hematocrit. After further investigation, including bone marrow biopsy, a diagnosis of polycythemia vera is confirmed., A routine blood test during an annual physical reveals an abnormally high hematocrit in a 50-year-old patient.Further testing, including genetic testing for JAK2 mutations, leads to a diagnosis of polycythemia vera., A patient with a known history of polycythemia vera presents with sudden chest pain and shortness of breath.This raises concern for a possible pulmonary embolism, a known complication of the condition.
Documentation should include complete blood count (CBC) results, bone marrow biopsy findings, genetic testing results (if performed), and a detailed description of the patient's symptoms and clinical presentation.
- Payment Status: Active
- Specialties:Hematology, Oncology
- Place of Service:Office, Inpatient Hospital, Outpatient Hospital