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2025 ICD-10-CM code D49

Neoplasm of unspecified behavior. This code is used when the behavior of the neoplasm (whether benign or malignant) is not specified or documented.

Use this code when the physician does not document the behavior of the neoplasm.Do not use this code if the behavior is documented as "uncertain."Refer to the Table of Neoplasms in ICD-10-CM to ensure the appropriate site-specific code is used once the behavior is determined.

Medical necessity for further diagnostic testing and/or treatment is established by the presence of a neoplasm of unspecified behavior.Determining the behavior of the neoplasm is necessary for appropriate management and treatment planning.

Symptoms vary depending on the neoplasm and its location but can include pain and/or organ dysfunction. Diagnosis is based on patient history, examination, and diagnostic studies, which can include blood tests, cytology, histology, imaging (ultrasound, CT, MRI, PET), endoscopy, cystoscopy, and biopsy. Treatment depends on the diagnosis and might involve surgery, chemotherapy, or radiation therapy.

In simple words: This code is used when a doctor finds a growth or tumor but doesn't know yet if it's cancerous or not, and hasn't specified its behavior.More tests may be needed to figure that out.

Neoplasms of unspecified behavior refer to growths, new growths, neoplasms, or tumors (but not masses or lumps) where the provider does not have enough information to determine whether they are benign or malignant, or simply does not document it.Includes: 'growth' NOS, neoplasm NOS, new growth NOS, tumor NOS. Excludes1: neoplasms of uncertain behavior (D37-D44, D48)

Example 1: A patient presents with a lump under their skin. The physician performs a biopsy, but the pathology report is inconclusive, stating "neoplasm, NOS."Since the behavior (benign or malignant) is not specified, D49 is used., A patient's imaging reveals a growth in the liver described as a "tumor" with no further details.Because the behavior is not documented as benign or malignant, D49 would be applicable until more information is obtained. , During surgery, a surgeon finds an unexpected growth.They document it as a "new growth" but do not provide details on malignancy.Since there is no specification of the neoplasm's behavior, D49 is used as a placeholder until further investigation can be done.

Documentation should include the location of the neoplasm, any associated symptoms, and details of diagnostic studies performed. The provider's statement that the neoplasm behavior is unspecified or unknown should be clear.

** Distinguishing between "unspecified" and "uncertain" behavior is crucial for correct coding. "Unspecified" implies a lack of information, while "uncertain" indicates that the behavior cannot be determined despite investigation. D49 should not be used for masses or lumps unless documented as neoplastic.It is important to follow up on the final diagnosis after further evaluation.

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