In simple words: This code refers to other types of sickle cell disease. Sickle cell disease is a genetic condition where red blood cells become misshapen, like sickles.This can cause problems like anemia, pain, and infections.

This ICD-10-CM code identifies a patient with a sickle cell disorder that is not specifically classified elsewhere in the D57 category. This includes conditions like Hb-SD disease and Hb-SE disease, which are variations of sickle cell disease resulting from the inheritance of different combinations of abnormal hemoglobin genes.

Example 1: A 5-year-old patient presents with fatigue, jaundice, and swollen hands and feet.Blood tests reveal sickle-shaped red blood cells and a diagnosis of Hb-SD disease is confirmed, leading to the use of D57.8., A teenager experiences recurrent episodes of pain and anemia, and is subsequently diagnosed with Hb-SE disease after genetic testing, requiring the application of code D57.8., An adult with a history of mild anemia undergoes genetic testing, which reveals a previously undiagnosed sickle cell disorder not classified as sickle cell anemia (D57.0) or sickle cell trait (D57.1), resulting in the use of D57.8.

Documentation should specify the type of sickle cell disorder, such as Hb-SD or Hb-SE, and detail clinical findings, including symptoms, blood test results, and genetic testing results if available. Any associated conditions, such as acute chest syndrome or vaso-occlusive crises, should also be documented.