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2025 ICD-10-CM code D84.9

Unspecified immunodeficiency. This code is used when the provider does not document the specific type of immunodeficiency.

Use this code only when a more specific immunodeficiency diagnosis cannot be made. Always code any underlying conditions or causes of immunodeficiency if known.

Medical necessity is established by the clinical history of recurrent or unusual infections, coupled with the inability to identify a specific cause after appropriate testing.

A patient may present with recurring infections (respiratory, skin, gastrointestinal) and inflammation. Diagnosis is based on medical history, symptoms, physical exam, and tests like CBC, biopsy, immunoglobulin and complement levels, and genetic testing. Treatment varies depending on the specific disorder.

In simple words: This refers to a condition where the body's immune system isn't working as it should, making the person more vulnerable to infections, autoimmune problems, and cancer.The exact type of immunodeficiency isn't specified by the doctor.

Immunodeficiency, unspecified. Immunocompromised NOS. Immunodeficient NOS. Immunosuppressed NOS.

Example 1: A patient presents with recurrent pneumonia and other infections with no identified cause. After extensive testing, no specific immunodeficiency is diagnosed. The physician uses D84.9 to document the unspecified immunodeficiency., An infant is experiencing frequent and severe infections. Initial tests don't reveal a specific immunodeficiency disorder. D84.9 is used until further testing can be done or a specific diagnosis is made., A patient with a history of recurrent infections is seen by an infectious disease specialist. After a thorough evaluation, no specific immunodeficiency is found, and the patient is diagnosed with unspecified immunodeficiency (D84.9).

Documentation should include details of the recurrent infections, the results of tests ruling out specific immunodeficiencies, and any other relevant clinical findings.

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