2025 ICD-10-CM code E31
Polyglandular dysfunction.This condition involves dysfunction of multiple endocrine glands.
Medical necessity for treatment of polyglandular dysfunction is established by the presence of symptomatic hormone deficiencies and/or related conditions that impact the patient's health and quality of life.The need for hormone replacement therapies, immunosuppressants, or other treatments should be justified based on the individual patient's clinical presentation and the specific deficiencies identified.
Clinicians diagnose polyglandular dysfunction based on patient history, physical examination, and laboratory tests, including hormone level assessments.Treatment varies depending on the specific glands affected and may involve hormone replacement therapy, immunosuppressants, and management of specific symptoms like candidiasis.It's important to note that treating one hormone deficiency could exacerbate another if not diagnosed, so careful management is crucial.
- 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- E31 is part of the block E20-E35 which includes disorders of other endocrine glands.
In simple words: Polyglandular dysfunction means that several hormone-producing glands in your body aren't working correctly at the same time, usually because of a problem with your immune system. This can cause a variety of symptoms depending on which glands are affected.
Polyglandular dysfunction refers to the simultaneous dysfunction of multiple endocrine glands, typically due to an autoimmune cause.It is characterized by the presence of two or more endocrine disorders. Several types exist, each with a distinct set of affected glands and associated symptoms.
Example 1: A patient presents with chronic mucocutaneous candidiasis, hypoparathyroidism, and adrenal insufficiency. This combination points towards Type 1 polyglandular deficiency syndrome (APECED)., A 35-year-old female patient exhibits symptoms of adrenal insufficiency, hypothyroidism, and type 1 diabetes mellitus.This combination suggests Type 2 polyglandular deficiency syndrome (Schmidt syndrome)., A patient has hypothyroidism, pernicious anemia, type 1 diabetes mellitus, vitiligo, and alopecia. This combination suggests Type 3 polyglandular deficiency syndrome.
Documentation should include detailed patient history, physical exam findings, and results of laboratory tests, including hormone levels and autoantibody tests.If genetic testing is performed, the results should also be documented. The specific type of polyglandular dysfunction should be clearly stated, along with any associated conditions like candidiasis or specific organ involvement.
** Polyglandular dysfunction is a complex condition that requires careful monitoring and management due to the potential for various complications and the interplay between different hormone deficiencies.Genetic counseling may be beneficial for patients with Type 1 as it's inherited in an autosomal recessive pattern. As of today, November 30th, 2024, this information is current, but medical coding guidelines and best practices are subject to change. Always refer to the most up-to-date resources.
- Specialties:Endocrinology, Internal Medicine, Immunology, Genetics
- Place of Service:Office, Inpatient Hospital, Outpatient Hospital