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2025 ICD-10-CM code E35

Disorders of endocrine glands in diseases classified elsewhere. Code first the underlying disease.

E35 is a manifestation code and should never be sequenced first. The underlying disease causing the endocrine gland disorder must be coded before E35.Do not use E35 for endocrine disorders directly caused by infections like tuberculosis or syphilis of the endocrine gland itself, as these have specific codes.

Medical necessity for E35 is established by demonstrating a causal relationship between the underlying disease and the endocrine gland disorder. This requires documentation supporting the diagnosis of both conditions and evidence linking the endocrine dysfunction to the primary disease process.

The endocrine system includes organs that produce hormones which regulate bodily functions. A patient with endocrine gland disorders caused by other diseases experiences various symptoms depending on the affected hormones. Diagnosis involves patient history, physical exam, blood tests for hormone levels, and imaging studies like CT and MRI. Treatment addresses the underlying cause and symptom relief.

In simple words: This code describes a problem with an endocrine gland (like the thyroid, adrenal gland, or pancreas) that is caused by another disease.The other disease should be coded first.

Disorders of endocrine glands in diseases classified elsewhere. Code first underlying disease, such as: late congenital syphilis of thymus gland [Dubois disease] (A50.59). Use additional code, if applicable, to identify sequelae of tuberculosis of other organs (B90.8).

Example 1: A patient with late congenital syphilis (A50.59) presents with thymus gland dysfunction. E35 is used as a secondary code after A50.59 to indicate the endocrine gland disorder resulting from syphilis., A patient with tuberculosis sequelae (B90.8) develops adrenal insufficiency. B90.8 is coded first, followed by E35 to specify the adrenal gland disorder due to tuberculosis., A patient with sarcoidosis (I69.0) experiences parathyroid dysfunction. I69.0 is listed first, and E35 is added to indicate the endocrine gland involvement caused by sarcoidosis.

Documentation should clearly establish the underlying disease causing the endocrine gland disorder. Medical records should include the diagnosis of both the primary condition and the resulting endocrine dysfunction, along with relevant clinical findings, lab results, and imaging studies.

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