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BETA v.3.0

2025 ICD-10-CM code E53

Deficiency of other B group vitamins. This excludes sequelae of vitamin B deficiency (E64.8).

Code E53 is used for deficiencies of B group vitamins other than B1 (thiamine), B9 (folate), and B12 (cobalamin), which have their own specific codes.It is important to note that neoplasms causing functional activity or hyper/hypofunction of endocrine glands should be coded according to Chapter 2 guidelines, with E53 used as an additional code if applicable.Transitory endocrine and metabolic disorders specific to newborns are excluded and should be coded using P70-P74.

Medical necessity for treating a B vitamin deficiency is established by the presence of signs, symptoms, and/or laboratory findings indicative of the specific deficiency.

Deficiency of other B group vitamins is generally due to chronic alcohol use, bariatric surgery, malabsorption, lack of proper diet, and oral contraceptive use. Symptoms vary based on the deficiency, but may include anemia, fatigue, weakness and pain in the limbs, weight loss, headaches, dizziness, confusion, dry skin and brittle nails and hair, memory loss, cognitive abnormalities, numbness and tingling in the extremities, diarrhea, and even death.

In simple words: This code indicates a deficiency in B vitamins other than B1, B9, and B12, which have their own specific codes. B vitamins are essential nutrients that help your body convert food into energy, among other functions.A deficiency can lead to various health problems depending on the specific B vitamin that is lacking.

Deficiency of other B group vitamins refers to a nutritional deficiency caused by inadequate intake of vitamins in the B group. These eight essential water-soluble vitamins are crucial for converting carbohydrates into glucose and breaking down fats and proteins. This code is used when the provider documents a deficiency of a B group vitamin, such as riboflavin (B2), pyridoxine (B6), or other B vitamins not represented by another, more specific code.

Example 1: A patient presents with fatigue, cracked lips, and a swollen tongue. Blood tests reveal a riboflavin (B2) deficiency. The physician documents "riboflavin deficiency." Code E53 is assigned., A patient with a history of chronic alcohol abuse exhibits confusion, irritability, and poor coordination.After further examination, a diagnosis of pyridoxine (B6) deficiency is made. Code E53 is assigned., A patient who recently underwent bariatric surgery experiences peripheral neuropathy (numbness and tingling in the hands and feet).Testing shows a deficiency in multiple B vitamins, including B6. Because B1, B9, and B12 are not deficient, code E53 is assigned.

Documentation should include the specific B vitamin deficiency (e.g., riboflavin, pyridoxine), signs and symptoms supporting the diagnosis, and any underlying conditions contributing to the deficiency (e.g., alcohol abuse, malabsorption).

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