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2025 ICD-10-CM code F33.3

Recurrent major depressive disorder, severe, with psychotic symptoms.

The psychotic features must be present during the current major depressive episode.If the psychosis is due to a separate medical condition or substance use, then that condition should be coded separately. If the patient is in remission, F33.4- should be used.

Medical necessity for this code must be supported by documentation that demonstrates the severity of the depression, the presence of psychotic symptoms, and the significant impact on the patient's functioning.The documentation should clearly justify the need for medical intervention.

Diagnosis requires assessment by a mental health professional based on DSM-5 criteria, medical history, symptoms, a detailed inquiry into personal and social behavior, and a physical examination. Symptoms include severely depressed mood, loss of interest/pleasure, emotional distress, difficulty concentrating, fatigue, cognitive defects, sleep disturbances, feelings of worthlessness or guilt, delusions, and hallucinations. Treatment may include antidepressants, antipsychotics, psychotherapy (such as cognitive therapy), electroconvulsive therapy (ECT), or other brain stimulation therapies.

In simple words: This diagnosis means someone has had several serious episodes of depression, and during this current episode, they're experiencing a severely depressed mood with hallucinations or delusions.Their depression is impacting their daily life significantly.

This code describes a severe, recurrent episode of major depressive disorder characterized by the presence of psychotic symptoms such as delusions or hallucinations. It signifies that the patient has experienced at least two major depressive episodes separated by a period of at least two months of normal function.The current episode is classified as severe, indicating significant functional impairment. The psychotic features may be mood-congruent (consistent with the depressive mood) or mood-incongruent.

Example 1: A patient with a history of major depression presents with severely depressed mood, loss of interest in activities, fatigue, and reports hearing voices telling them they are worthless. This is their second major depressive episode in three years., A patient experiences a recurrence of major depression, now with the delusion that they are being persecuted by a government agency.They also exhibit loss of appetite, insomnia, and difficulty concentrating.This is their third such episode., A patient with recurrent major depression is hospitalized due to suicidal ideation. During the episode, the patient displays severe psychomotor retardation and the delusion that their organs are failing.

Documentation should include: Detailed history of present illness including onset, duration, and severity of symptoms; Past psychiatric history including previous diagnoses and treatments; Mental status examination findings; Description of psychotic symptoms (e.g., delusions, hallucinations); Assessment of functional impairment (social, occupational); Results of any relevant diagnostic tests (to rule out other medical conditions); Treatment plan including medication, therapy, and other interventions.

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