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2025 ICD-10-CM code F43.23

Adjustment disorder with mixed anxiety and depressed mood. This occurs when a patient exhibits maladaptive reactions to an identifiable stressor, presenting with a combination of anxiety and depressed mood within three months of the stressor.

The diagnosis should specify the mixed presentation of anxiety and depressed mood and differentiate it from other mental health disorders or normal bereavement.

Medical necessity is established by demonstrating the impact of the mixed anxiety and depressed mood on the patient's functioning and the direct relationship between the symptoms and the identified stressor.

Diagnosed by mental health professionals or other providers based on DSM-5 criteria, patient history, signs and symptoms, and a detailed inquiry into the patient's personal and social behaviors, and physical examination. Treatment may involve medication (antidepressants, anxiolytics), psychological counseling (CBT), and supportive care.

In simple words: This is a condition where someone has trouble coping with a stressful life event, leading to a mix of anxiety and depression.They might feel nervous, worried, sad, and hopeless. These feelings are stronger than what would be expected given the situation and make it hard to function normally.

Adjustment disorder with mixed anxiety and depressed mood is a condition characterized by emotional or behavioral symptoms in response to an identifiable stressor within three months of its onset.Symptoms, which include a mix of anxiety (nervousness, worry) and depression (low mood, hopelessness, tearfulness), are disproportionate to the stressor's severity and cause significant impairment in social, occupational, or other important areas of functioning. The symptoms do not persist for more than six months after the stressor or its consequences have ceased.This diagnosis requires careful differentiation from normal bereavement and other mental disorders with similar symptoms.

Example 1: A 35-year-old individual experiences job loss and develops difficulty sleeping, anxiety, tearfulness, and feelings of hopelessness within two months of the event.These symptoms significantly impact their daily functioning., A student experiences significant academic pressure and develops excessive worrying, irritability, poor appetite, and withdrawal from social activities within three months.These symptoms are out of proportion to the stressor and affect their academic performance., A person experiences a difficult divorce and exhibits restlessness, difficulty concentrating, poor appetite, hopelessness, and avoids social interaction. These symptoms occur within one month of the divorce being finalized and impact personal and professional functioning.

Documentation should include: the identifiable stressor, onset of symptoms within three months of the stressor, mixed presentation of anxiety and depressive symptoms, clinical evidence demonstrating that the symptoms are excessive given the stressor, and impact on the patient's functioning.

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