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2025 ICD-10-CM code G93.7

Reye's syndrome. Code first poisoning due to salicylates, if applicable (T39.0-, with sixth character 1-4). Use additional code for adverse effect due to salicylates, if applicable (T39.0-, with sixth character 5).

Code first any underlying cause, such as salicylate poisoning (T39.0-), if applicable.

Medical necessity is established by the clinical presentation of signs and symptoms consistent with Reye's syndrome, particularly following a recent viral infection and possible aspirin use. The rare and serious nature of the condition necessitates prompt diagnosis and treatment to prevent severe complications.

Diagnosis is based on medical history, physical exam, and symptoms.While no single test confirms Reye's syndrome, tests such as spinal tap, liver biopsy, CT scan, MRI, and skin biopsy may be ordered. Treatment often includes IV fluids, diuretics, medications to prevent bleeding, and cooling blankets. The exact cause is unknown, but it's linked to aspirin use during viral infections like influenza and chickenpox, especially in children and teens.

IMPORTANT:If Reye's syndrome is due to salicylate poisoning, code the poisoning first (T39.0- with sixth character 1-4).Additionally, use a code for the adverse effect of salicylates if applicable (T39.0- with the sixth character 5).

In simple words: Reye's syndrome is a rare but serious illness that causes swelling in the liver and brain. It usually happens after a viral infection like the flu or chickenpox, especially if aspirin has been taken. Symptoms can include vomiting, confusion, sleepiness, and seizures. It's important to get medical help right away if these symptoms appear after a viral illness.

Reye’s syndrome is a rare, serious condition characterized by swelling in the liver and brain. It typically develops between 12 hours and 3 weeks after recovery from a viral illness, such as an upper respiratory tract infection or gastroenteritis. Symptoms include persistent vomiting, confusion, lethargy, disorientation, hyperreflexia, hyperventilation, and tachycardia, which can rapidly progress to seizures, non-inflammatory encephalopathy, coma, and death.Associated findings include hepatomegaly, acute hepatic steatosis, fatty liver degeneration, and multiple laboratory abnormalities.

Example 1: A 5-year-old child presents with persistent vomiting, lethargy, and confusion three days after recovering from chickenpox. The child was given aspirin during the infection.The physician suspects Reye's syndrome and orders a liver biopsy and CT scan to support the diagnosis., A teenager experiences seizures and altered mental status following a recent bout of the flu.They report taking aspirin for their symptoms. The clinical picture and lab results point to a diagnosis of Reye's syndrome. , An infant presents with diarrhea and rapid breathing a few days after a viral infection. Further examination reveals liver dysfunction, raising suspicion for Reye's syndrome, although it's less common at this age.

Complete medical history including recent infections and medication use (especially aspirin), physical exam findings (e.g., hepatomegaly, altered mental status), and results of diagnostic tests (e.g., liver function tests, CT/MRI scans, biopsies) if performed.

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