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2025 ICD-10-CM code K71.1

Toxic liver disease with hepatic necrosis.

Always code the underlying cause of the toxic liver disease (e.g., specific medication) using additional codes as necessary.Follow the guidelines for poisoning and adverse effects as detailed in the ICD-10-CM coding manual.

Medical necessity is established by documentation of clinical findings consistent with toxic liver disease with hepatic necrosis. This includes abnormal liver function tests, imaging showing liver damage, and in many cases, a liver biopsy confirms the diagnosis.The treatment plan should be based on the severity of liver failure and the underlying cause.The necessity for specific procedures or treatments must be documented.

Hepatologist, Gastroenterologist, Internist, or other physician managing liver diseases. The clinical responsibility includes diagnosis, treatment, and monitoring of liver function.

IMPORTANT:Code first for poisoning due to drug or toxin (T36-T65 with 5th or 6th character 1-4) and use additional code for adverse effect (T36-T50 with 5th or 6th character 5) if applicable.

In simple words: This code is for liver damage caused by poisonous substances, particularly medications, leading to liver cell death.It covers both cases where the reaction is unexpected and cases where it is anticipated based on the drug's properties.This condition can cause acute or long-term liver failure.

This code describes toxic liver disease, specifically instances resulting in hepatic necrosis.It encompasses both drug-induced idiosyncratic (unpredictable) and drug-induced toxic (predictable) liver damage.The code includes acute or chronic hepatic failure due to drug exposure.It excludes alcoholic liver disease, Budd-Chiari syndrome, hemochromatosis, Reye's syndrome, viral hepatitis, and Wilson's disease.Further coding is required for poisoning due to drugs or toxins, using codes T36-T65 with fifth or sixth character 1-4, and for adverse effects using codes T36-T50 with fifth or sixth character 5.

Example 1: A 60-year-old woman develops acute liver failure after starting a new medication for arthritis. Liver biopsy shows evidence of drug-induced hepatic necrosis., A 45-year-old man with a history of alcohol abuse develops chronic liver disease, and a medication he is taking exacerbates existing liver damage. Tests reveal hepatic necrosis, consistent with toxic liver disease., A 30-year-old woman is diagnosed with an idiosyncratic reaction to a commonly prescribed antibiotic.Liver function tests and imaging show signs of drug-induced liver failure leading to hepatic necrosis.

Complete medical history, including medication list and dosages; comprehensive physical examination focusing on liver assessment; liver function tests (AST, ALT, bilirubin, alkaline phosphatase); imaging studies (ultrasound, CT scan, MRI); liver biopsy with histopathological examination; documentation of any adverse effects or symptoms; laboratory results showing abnormal liver enzymes.

** Consider using additional codes to specify the specific drug causing the liver damage and any complications arising from the hepatic necrosis.Always consult the latest ICD-10-CM coding guidelines for the most up-to-date information.

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