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2025 ICD-10-CM code K72.01

Acute and subacute hepatic failure with coma.

Always code the underlying cause of the hepatic failure, if known.Do not code K72.01 if the patient presents with hepatic encephalopathy but without coma.

Modifiers may be applicable depending on the circumstances of the encounter and the services provided.

Medical necessity for the diagnosis is established by the presence of acute or subacute hepatic failure with documented hepatic coma (loss of consciousness secondary to liver failure). This necessitates immediate medical intervention and hospitalization for supportive care.

The clinical responsibility for a patient with K72.01 would involve a multidisciplinary team, including hepatologists, intensivists, and neurologists.Treatment would focus on supportive care, addressing the underlying cause of liver failure, and managing hepatic encephalopathy.

IMPORTANT:Excludes1:Jaundice NOS (R17), Hemochromatosis (E83.11-), Reye's syndrome (G93.7), Viral hepatitis (B15-B19), Wilson's disease (E83.01).Excludes2: Hepatic failure complicating abortion or ectopic or molar pregnancy (O00-O07, O08.8), hepatic failure complicating pregnancy, childbirth, and the puerperium (O26.6-), viral hepatitis with hepatic coma (B15-B19).Also excludes alcoholic hepatic failure (K70.4), hepatic failure with toxic liver disease (K71.1-), icterus of newborn (P55-P59), postprocedural hepatic failure (K91.82).Note that K72.00 (Acute and subacute hepatic failure without coma) should be used when coma is absent.

In simple words: This code describes a serious condition where the liver suddenly stops working properly, causing the patient to lose consciousness and fall into a coma.

This ICD-10-CM code signifies acute and subacute hepatic failure complicated by coma.It encompasses conditions where liver function deteriorates rapidly, leading to encephalopathy and loss of consciousness.The code specifically includes cases with coma, differentiating it from codes representing hepatic failure without coma.This code should only be used when hepatic coma is present.

Example 1: A 40-year-old patient presents with acute liver failure secondary to acetaminophen overdose, progressing to hepatic coma requiring intensive care unit (ICU) admission., A 65-year-old patient with cirrhosis develops acute-on-chronic liver failure, precipitating hepatic encephalopathy and coma, necessitating emergency liver transplantation., A 25-year-old patient with fulminant hepatitis B develops hepatic failure with coma, requiring aggressive supportive care and close monitoring.

Detailed history and physical examination, laboratory results including liver function tests (LFTs), blood ammonia levels, coagulation studies, imaging studies (ultrasound, CT scan), and neurological assessment documenting the level of consciousness and neurological signs.

** Accurate coding requires careful documentation of the patient's clinical presentation and the severity of liver failure. The presence of coma is crucial for assigning K72.01.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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