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2025 ICD-10-CM code L27.1

Localized skin eruption due to drugs and medicaments taken internally.

Code L27.1 should be used when the skin eruption is localized. If the reaction is generalized, other codes within the L27 category might be more appropriate.If the drug causing the reaction is known, an additional code from the T36-T50 category should be used to specify the drug.

Medical necessity is established by the presence of a skin eruption temporally related to the ingestion of a drug or medication, where other causes have been reasonably excluded. The documentation should clearly support the diagnosis and the causal relationship between the medication and the reaction.

Clinicians should document the characteristics of the skin eruption, the medication(s) suspected of causing the reaction, and any other relevant medical history.It is crucial to distinguish this condition from other forms of dermatitis and to accurately identify the causative drug if possible.

In simple words: This code represents a localized skin rash or eruption caused by medications taken by mouth.

Localized skin eruption due to drugs and medicaments taken internally. Use additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Example 1: A patient presents with a localized rash on their arm after starting a new antibiotic. The rash is determined to be an allergic reaction to the medication., A patient develops hives on their torso after taking a pain reliever.The hives are localized and considered a drug eruption., A patient experiences a localized itchy rash after taking a new prescription medication for high blood pressure. The reaction is documented as a localized drug eruption.

Detailed description of the skin eruption (location, appearance, associated symptoms).Name and dosage of the suspected drug. Temporal relationship between starting the medication and the onset of the rash.Other potential causes ruled out, such as contact dermatitis or other allergies.

** Excludes1: allergy NOS (T78.40)Excludes2: adverse food reaction, except dermatitis (T78.0-T78.1), contact dermatitis (L23-L25), drug photoallergic response (L56.1), drug phototoxic response (L56.0), urticaria (L50.-)Parent Code: L27

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