In simple words: Stevens-Johnson Syndrome is a rare, serious reaction, usually to a medicine.It causes flu-like symptoms and a painful rash that blisters and makes the skin peel off.It needs treatment in a hospital.

Stevens-Johnson syndrome (SJS) is a rare and serious disorder of the skin and mucous membranes. It's typically a reaction to medication, starting with flu-like symptoms followed by a painful, spreading rash that blisters. Subsequently, the top layer of affected skin dies, sheds, and begins to heal. SJS is a medical emergency requiring hospitalization. It involves less than 10% total body skin area separation of the dermis.A more severe form, toxic epidermal necrolysis (TEN), affects more than 30% of the skin surface.

Example 1: A patient presents with flu-like symptoms and a rapidly spreading, painful rash with blisters after starting a new antibiotic. Less than 10% of the body surface area is affected. The diagnosis is Stevens-Johnson syndrome., A child develops a severe rash with blisters and skin detachment after taking an anticonvulsant medication. The affected area is less than 10% of their body surface, indicating Stevens-Johnson syndrome. , A patient with a history of herpes simplex virus develops a widespread painful rash, blisters, and skin sloughing involving a small percentage of their body. They are diagnosed with Stevens-Johnson syndrome potentially triggered by the viral infection.

Documentation should include the extent of skin and mucous membrane involvement (less than 10% for SJS), description of the rash and blisters, presence of any systemic symptoms (fever, malaise), medication history, and suspected causative agent (medication, infection). Photographs may also be helpful.