2025 ICD-10-CM code N14.0
(Active) Effective Date: N/A Revision Date: N/A Deletion Date: N/A Diseases of the genitourinary system - Renal tubulo-interstitial diseases Diseases of the genitourinary system (N00-N99) Feed
Analgesic nephropathy is kidney damage caused by long-term use of certain pain relievers.
Medical necessity for this diagnosis code is established through documentation supporting chronic kidney injury due to long-term analgesic use. This typically requires laboratory evidence of reduced kidney function, plus a detailed history documenting the pattern and duration of analgesic use.The relationship between the analgesic use and kidney injury must be clinically established.
Diagnosis and management of analgesic nephropathy; may involve nephrology consultation, medication adjustment, and supportive care.
- Diseases of the genitourinary system (N00-N99)
- N14- Drug and heavy-metal induced tubulo-interstitial and tubular conditions
In simple words: This code means you have kidney damage from taking too much pain medicine for a long time.Your kidneys aren't working as well as they should.
Analgesic nephropathy (N14.0) is a form of chronic tubulointerstitial nephritis resulting from the long-term use of analgesics, particularly nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen.It is characterized by damage to the renal tubules and interstitium, leading to impaired kidney function. The diagnosis requires a history of analgesic overuse and clinical or laboratory evidence of renal impairment.Specific findings may include proteinuria, hematuria, and reduced glomerular filtration rate.
Example 1: A 65-year-old patient with a long history of chronic back pain presents with worsening fatigue, edema, and decreased urine output.Their history reveals daily use of over-the-counter NSAIDs for many years.Laboratory tests show reduced creatinine clearance and proteinuria.Diagnosis of analgesic nephropathy is made., A 70-year-old patient with a history of osteoarthritis and long-term use of acetaminophen is found to have elevated serum creatinine and reduced glomerular filtration rate on routine blood work. Urinalysis confirms proteinuria and microscopic hematuria. Further investigation points to analgesic nephropathy., A 50-year-old patient is referred to nephrology due to persistent kidney problems.History reveals that the patient had been taking large doses of several NSAIDs regularly for 20 years, after a severe injury. The nephrologist diagnoses analgesic nephropathy based on laboratory data showing reduced kidney function.
* Detailed patient history, including medication history with specific dosages and duration of use.* Physical examination findings.* Laboratory results including serum creatinine, blood urea nitrogen (BUN), glomerular filtration rate (GFR), urinalysis, and possibly kidney biopsy.
** Analgesic nephropathy can be difficult to distinguish from other forms of chronic kidney disease.A kidney biopsy may be necessary in some cases to confirm the diagnosis and rule out other etiologies.
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- Specialties:Nephrology, Internal Medicine, Rheumatology
- Place of Service:Office, Hospital, Outpatient setting