In simple words: The presence of endometrial tissue (the lining of the uterus) in the sigmoid colon (part of the large intestine), without specifying how deep the tissue has penetrated.

Endometriosis of the sigmoid colon, unspecified depth.

Example 1: A 35-year-old female patient presents with chronic pelvic pain, painful bowel movements, and cyclical rectal bleeding. During a laparoscopy, endometrial tissue is found in the sigmoid colon, but the depth of infiltration is not specified. The diagnosis is N80.529., A patient undergoes a colonoscopy for evaluation of iron-deficiency anemia.Biopsies reveal the presence of endometrial glands and stroma within the sigmoid colon wall, with the depth of invasion not clearly determined. N80.529 is coded as a secondary diagnosis., A woman with a known history of endometriosis undergoes imaging studies for abdominal pain.The imaging suggests the involvement of the sigmoid colon with endometriosis, but the depth of penetration cannot be determined based on the available images. The diagnosis of N80.529 is confirmed during surgery.

Medical records should document the presence of endometriosis in the sigmoid colon, including supporting evidence from imaging studies (e.g. ultrasound, MRI), laparoscopy, or histopathology reports from colonoscopy/biopsy specimens. The documentation should include the location and extent of endometrial implants where possible.