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2025 ICD-10-CM code O21.1

Hyperemesis gravidarum with metabolic disturbance. This condition involves severe nausea and vomiting during pregnancy, leading to metabolic imbalances like dehydration or electrolyte disturbances.

Use additional code from category Z3A, Weeks of gestation, to identify the specific week of the pregnancy, if known.Do not use this code on newborn records.

Medical necessity for the diagnosis and treatment of hyperemesis gravidarum with metabolic disturbance is established by the presence of severe nausea and vomiting that significantly impacts the patient's health and well-being, leading to complications such as dehydration, electrolyte imbalances, and nutritional deficiencies.

Physicians, including obstetricians and gynecologists (OB/GYNs), are responsible for diagnosing and managing hyperemesis gravidarum with metabolic disturbance.This includes evaluating the severity of the condition, monitoring electrolyte levels, and providing appropriate treatment, such as intravenous fluids, medications, and nutritional support.

In simple words: Severe morning sickness with complications due to dehydration and loss of nutrients.

Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as carbohydrate depletion, dehydration, or electrolyte imbalance.

Example 1: A 25-year-old woman in her first trimester presents with persistent nausea and vomiting, weight loss, and dehydration. Laboratory tests reveal electrolyte imbalances, leading to a diagnosis of hyperemesis gravidarum with metabolic disturbance., A 30-year-old woman in her second trimester experiences severe nausea and vomiting, unable to keep down any food or fluids. She develops ketonuria and requires hospitalization for intravenous fluid and electrolyte replacement., A 28-year-old woman with a history of hyperemesis gravidarum in a previous pregnancy presents with similar symptoms in her current pregnancy. Early intervention with antiemetic medication and nutritional support helps prevent severe metabolic disturbance.

Documentation should include details of the onset and duration of nausea and vomiting, any associated symptoms like weight loss or dehydration, laboratory results showing electrolyte imbalances, and the treatment provided.

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