In simple words: Infection of the amniotic sac and fluid during the second trimester of pregnancy (weeks 14-27).

Chorioamnionitis, second trimester, not applicable or unspecified. This code is specific to a patient in their second trimester of pregnancy (14 weeks 0 days to less than 28 weeks 0 days) experiencing chorioamnionitis. Chorioamnionitis is an infection of the fetal membranes (amnion and chorion) and amniotic fluid, typically caused by ascending bacteria from the vagina. It's a serious condition that can lead to preterm labor and complications for both mother and fetus.

Example 1: A 22-year-old woman at 20 weeks gestation presents with fever, uterine tenderness, and fetal tachycardia. Vaginal examination reveals purulent discharge. Lab tests indicate an elevated white blood cell count. Diagnosis: Chorioamnionitis., A 30-year-old woman, G2P1, at 16 weeks gestation, presents with lower abdominal pain, fever, and chills. She has premature rupture of membranes. Amniotic fluid analysis reveals bacteria. Diagnosis: Chorioamnionitis., A 25-year-old woman at 24 weeks gestation is admitted with fever, elevated white blood cell count, and uterine tenderness. Fetal heart rate monitoring shows tachycardia. A diagnosis of chorioamnionitis is made after ruling out other causes of infection.

Documentation should include signs and symptoms such as fever, maternal tachycardia, fetal tachycardia, uterine tenderness, and foul-smelling amniotic fluid. Laboratory findings like an elevated white blood cell count and positive amniotic fluid cultures confirm the diagnosis. The gestational age should be clearly documented as falling within the second trimester (14-27 weeks).