2025 ICD-10-CM code Q98.6
Male with structurally abnormal sex chromosome.
Medical necessity for genetic testing and subsequent management is established by the presence of signs, symptoms, or other clinical indications suggestive of a sex chromosome abnormality.This can include developmental delays, ambiguous genitalia, infertility, or other related health concerns.
Clinical responsibility for diagnosing and managing this condition typically falls under the purview of geneticists, genetic counselors, and/or endocrinologists.They are responsible for interpreting karyotype analysis, providing genetic counseling to patients and families, and managing any associated health concerns arising from the chromosomal abnormality.
In simple words: This code indicates a male has a structural problem with their sex chromosomes.
This code signifies the presence of a structural abnormality within the sex chromosomes of a male individual. This encompasses a range of potential chromosomal anomalies, excluding specific conditions like Klinefelter syndrome or 47,XYY karyotype, which have their own designated codes within the Q98 series.
Example 1: A newborn male undergoes genetic screening which reveals a structural abnormality in his sex chromosome. This abnormality is not consistent with known syndromes like Klinefelter's. The diagnosis is coded as Q98.6., An adolescent male presents with developmental delays and learning disabilities. Karyotyping shows a structurally abnormal sex chromosome, excluding common abnormalities. Q98.6 is used for this diagnosis., A male infant displays ambiguous genitalia. Genetic testing reveals a complex structural rearrangement involving a sex chromosome. After ruling out other specific disorders, the diagnosis is coded as Q98.6.
Documentation should include the results of karyotype analysis clearly describing the specific structural abnormality in the sex chromosome.Clinical findings and any associated phenotypic manifestations should also be documented. If genetic counseling has been provided, this should be noted as well.
- Specialties:Genetics, Endocrinology, Pediatrics, Urology
- Place of Service:Inpatient Hospital, Outpatient Hospital, Office, Independent Clinic