In simple words: Isolated proteinuria means there's protein in your urine, but no other kidney problems have been found yet.

Isolated proteinuria is the presence of an abnormal amount of protein in the urine without any other diagnosed kidney condition. This can be a transient finding or may indicate underlying kidney disease that requires further investigation.

Example 1: A 25-year-old patient presents for a routine physical exam. Urinalysis reveals elevated protein levels, but the patient is otherwise asymptomatic and has no history of kidney disease.R80.0 is used to document this finding., A 50-year-old patient with hypertension undergoes routine urine testing, which shows persistent proteinuria.Further evaluation, including blood tests and kidney imaging, is recommended to assess kidney function and rule out underlying kidney damage. R80.0 would be used initially, with more specific codes potentially added later., A 30-year-old patient presents with fever, fatigue, and recent weight gain.Urine analysis reveals proteinuria and other abnormalities.After further evaluation, the patient is diagnosed with lupus nephritis.R80.0 is not used, as a more specific code for lupus nephritis is assigned.

Documentation should include the results of the urinalysis showing elevated protein levels, any relevant signs or symptoms, past medical history related to kidney health, family history of kidney disease, medications, and the results of any further investigations.

** Isolated proteinuria can be classified as orthostatic or persistent. Orthostatic proteinuria is characterized by protein in the urine only when the patient is in an upright position, while persistent proteinuria is present regardless of the patient’s position. Further evaluation is necessary to determine the clinical significance and underlying cause of proteinuria.