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2025 ICD-10-CM code T42.4

Poisoning by, adverse effect of, and underdosing of benzodiazepines.

Use secondary codes from Chapter 20 (External causes of morbidity) to indicate the cause of the injury (e.g., accidental poisoning, intentional self-harm).If a retained foreign body is applicable, use code Z18.-.

Medical necessity must be established for any treatment provided due to poisoning, adverse effects, or underdosing.Documentation should support the need for the services rendered based on the patient's clinical condition.

The clinician is responsible for documenting the specific benzodiazepine involved, the route of administration, the circumstances of the poisoning or adverse effect, and the clinical manifestations.For underdosing, the prescribed dosage and the actual dosage taken should be noted.

In simple words: This code refers to health problems caused by taking too much, too little, or the wrong dose of a benzodiazepine medication, or having a bad reaction to it.

This code encompasses poisoning by, adverse effects of, and underdosing of benzodiazepines.It includes scenarios where the correct substance was properly administered but resulted in an adverse effect, overdose of the substance, the wrong substance given or taken in error, and underdosing due to inadvertently or deliberately taking less than prescribed.

Example 1: A patient intentionally overdoses on diazepam and presents to the emergency department with respiratory depression., A patient experiences an allergic reaction (e.g., skin rash) after taking lorazepam as prescribed., A patient with anxiety disorder mistakenly takes alprazolam twice in one day, resulting in excessive sedation.

Documentation should include the specific benzodiazepine involved, the route of exposure (ingestion, injection, etc.), the dosage or estimated amount if known,timing of exposure, clinical manifestations, and any treatment provided.For adverse effects, document the specific reaction and its severity.For underdosing,document the prescribed dosage, actual amount taken, and reason for underdosing.

** Excludes1: birth trauma (P10-P15), obstetric trauma (O70-O71)Excludes2: abuse and dependence of psychoactive substances (F10-F19), abuse of non-dependence-producing substances (F55.-), immunodeficiency due to drugs (D84.821), drug reaction and poisoning affecting newborn (P00-P96), pathological drug intoxication (inebriation) (F10-F19)Use additional code(s) to specify manifestations of poisoning.For adverse effects, code first the nature of the adverse effect.The drug giving rise to the adverse effect should be identified using codes from categories T36-T50 with fifth or sixth character 5.

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