2025 ICD-10-CM code Z17.0
(Active) Effective Date: N/A Factors influencing health status and contact with health services - Estrogen receptor status Z00-Z99 Feed
Estrogen receptor positive status [ER+]. This code indicates a positive status for estrogen receptors.
No modifiers are applicable to Z codes.
Medical necessity for the use of Z17.0 relates to its role in guiding treatment decisions for patients with estrogen receptor-positive tumors, primarily breast and ovarian cancers. Establishing ER status is essential for determining the appropriateness and potential effectiveness of hormone therapies, which can significantly improve outcomes for these patients.
The clinician's responsibility is to order the appropriate test for estrogen receptor status (such as an immunohistochemical assay on a tissue sample) and interpret the results in the context of the patient's overall clinical presentation, particularly in cases of breast cancer or ovarian cancer.This information is crucial for making treatment decisions, as hormone therapies might be beneficial for ER-positive tumors.
In simple words: This code means that your cells have tested positive for estrogen receptors, which are like little docking stations for the hormone estrogen. This information helps doctors understand how your condition might respond to treatments that affect estrogen.
Estrogen receptor positive status [ER+] is a medical classification indicating that cells in a tissue sample, typically from a breast tumor biopsy, have tested positive for the presence of estrogen receptors.These receptors are proteins within cells that bind to estrogen, influencing cell growth.A positive result suggests that the tumor's growth may be fueled by estrogen and may respond to hormone therapies that block estrogen's effects.
Example 1: A 55-year-old female patient diagnosed with invasive ductal carcinoma of the breast undergoes a biopsy. The pathology report confirms the diagnosis and additionally indicates that the tumor cells are estrogen receptor positive. The Z17.0 code is used to document the ER-positive status, alongside the appropriate code for the breast cancer diagnosis (e.g., C50.-)., A 60-year-old female is diagnosed with ovarian cancer. Biopsy results show the presence of estrogen receptors.Z17.0 is used in conjunction with the ovarian cancer code (e.g. C56.-) to reflect the hormone receptor status and guide treatment planning., A patient with a history of breast cancer is being monitored for recurrence.During a follow-up appointment, the physician reviews the patient's original pathology report, which indicated ER-positive status. Although the cancer is currently in remission, the Z17.0 code is still relevant and may be included in the patient's medical record to reflect this ongoing characteristic, which is important for long-term management and surveillance.
Documentation should clearly state the "estrogen receptor positive" status, typically derived from a pathology report following a biopsy or surgical excision of the tumor. The specific test method used to determine ER status (e.g., immunohistochemistry) should ideally be documented as well.The result should be quantitative, specifying the percentage of tumor cells staining positive for ER and the intensity of staining.
** This code is exempt from the Present on Admission (POA) reporting requirement. Always code the underlying malignancy as the principal diagnosis, followed by Z17.0 as a secondary code.
- Payment Status: Billable/Specific Code
- Specialties:Oncology, surgery, pathology, general practice
- Place of Service:Office, Inpatient Hospital, On Campus-Outpatient Hospital