Start New EnglishEspañol中文РусскийالعربيةTiếng ViệtFrançaisDeutsch한국어Tagalog Library Performance
BETA v.3.0

2025 CPT code 30100

Intranasal biopsy; removal of tissue sample from within the nasal cavity for examination.

Refer to the AMA CPT® manual and other relevant coding guidelines for specific instructions on the use of CPT code 30100.

Modifiers 22, 51, 52, 59, 76, 77, 78, 79 may be applicable depending on the circumstances of the procedure. Refer to the CPT guidelines for proper modifier usage.

Medical necessity is established when there is clinical suspicion of a nasal lesion, recurrent nosebleeds, or chronic sinusitis requiring histological evaluation for diagnosis and appropriate management.The biopsy must be deemed necessary by the physician based on the patient's clinical presentation and examination.

The physician is responsible for the preparation of the patient (including anesthesia), the insertion of nasal forceps, the removal of the tissue sample(s), and the sending of the sample(s) to the laboratory for pathological examination.They may also be responsible for suturing the biopsy site or allowing it to heal naturally.

IMPORTANT:For biopsy of skin of the nose, see codes 11102, 11103, 11104, 11105, 11106, and 11107.

In simple words: The doctor takes a small tissue sample from inside the nose to check for disease.A sample of healthy tissue is also taken for comparison. The sample is sent to a lab for testing.

This CPT code encompasses the procedure of obtaining an intranasal biopsy.The physician performs the biopsy after appropriate preparation and anesthesia of the patient. Using nasal forceps, a tissue sample is extracted from a suspicious or diseased area within the nasal cavity.Both the sample from the affected area and a sample of healthy intranasal tissue are sent to a pathologist for comparative analysis and further evaluation.The physician may suture the site or allow it to heal naturally.

Example 1: A patient presents with a suspicious nasal polyp. The physician performs an intranasal biopsy to determine if it is benign or malignant., A patient with recurrent nosebleeds undergoes an intranasal biopsy to rule out vascular abnormalities or other underlying causes., A patient with chronic sinusitis and suspected fungal infection undergoes an intranasal biopsy for fungal culture and microscopic examination.

* Detailed history and physical examination focusing on nasal symptoms.* Preoperative and postoperative notes documenting the procedure.* Pathology report with microscopic findings and diagnosis.* Anesthesia record if general or local anesthesia used.* Images (if obtained) such as nasal endoscopy before and after biopsy.

** Always verify code selection with current payer guidelines and medical necessity criteria.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

Discover what matters.

iFrame™ AI's knowledge is aligned with and limited to the materials uploaded by users and should not be interpreted as medical, legal, or any other form of advice by iFrame™.