2025 CPT code 52287

Cystourethroscopy, with injection(s) for chemodenervation of the bladder. The supply of the chemodenervation agent is reported separately.

Report the specific J-code for the chemodenervation agent in addition to 52287.Do not report separately for anesthetic instilled by the surgeon.

Modifiers may be applicable in certain circumstances, such as increased procedural services (22), multiple procedures (51), or distinct procedural service (59). Refer to current CPT guidelines for modifier usage.

Medical necessity for 52287 is established when other conservative treatments for overactive bladder, such as behavioral therapies and medications, have been unsuccessful or are contraindicated.

The physician prepares the patient and administers anesthesia, then inserts a cystoscope into the bladder through the urethra to examine the urinary tract.The physician locates the overactive bladder muscles and injects a neurolytic drug to weaken the muscle and reduce overactivity.

In simple words: A procedure where a doctor examines the inside of your bladder with a small camera and injects medicine to help control bladder spasms.

The provider performs an examination of the interior of the bladder, the urethra, and the ureteric openings by means of a cystoscope. He then inserts a needle and injects a neurolytic drug into the bladder muscle to treat an overactive bladder.The supply of the chemodenervation agent is reported separately.

Example 1: A patient with overactive bladder, diagnosed via urodynamic testing, undergoes cystourethroscopy and injection of botulinum toxin (Botox) into the bladder wall., A patient with urge incontinence not responding to conservative treatments undergoes cystourethroscopy and injection of onabotulinumtoxinA into the bladder detrusor muscle., A patient with neurogenic detrusor overactivity experiences persistent urgency and frequency despite anticholinergic medications. They undergo 52287 for chemodenervation.

Documentation should include the diagnosis supporting medical necessity (e.g., overactive bladder, neurogenic bladder), pre-procedure evaluation, informed consent, details of the procedure including type of chemodenervation agent used, and post-procedure assessment.

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