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2025 CPT code 54065

Destruction of extensive penile lesions (e.g., condyloma, papilloma) via various methods (laser, electrosurgery, cryosurgery, chemosurgery).

For destruction or excision of lesions other than those specified, refer to the Integumentary System codes.

Modifiers may be applicable. Refer to current CPT guidelines for appropriate modifier usage.

Medical necessity must be established for this procedure.This may include documentation of symptoms, failed conservative treatments, interference with function, or risk of malignancy.

The physician prepares the patient, administers anesthesia (typically local), identifies the lesion(s), and performs the chosen destruction method. This may involve applying chemicals, using an electric current or laser, freezing with liquid nitrogen, or surgically removing the lesion(s).

IMPORTANT For less extensive lesions: 54050 (chemical), 54055 (electrodesiccation), 54056 (cryosurgery), 54057 (laser), 54060 (excision).

In simple words: This procedure involves removing or destroying widespread skin growths on the penis, such as warts or other lesions, using methods like freezing, burning, chemicals, or cutting them out.

The physician destroys one or more extensive skin lesions of the penis, such as condyloma acuminatum, papilloma, molluscum contagiosum, or herpetic vesicles. Various techniques are employed, including chemical destruction, electrodesiccation, cryosurgery, laser surgery, or surgical excision.For surgical excision, an incision is made around the lesion, the lesion is excised, and the incision is closed with absorbable sutures. Chemical, electrodesiccation, cryosurgery, and laser surgery methods do not typically require sutures.

Example 1: A patient presents with extensive condyloma acuminata on the penile shaft. The physician performs laser ablation to destroy the lesions., A patient has multiple, large molluscum contagiosum lesions on the penis. Cryosurgery is used to freeze and destroy the lesions., A patient with a history of herpes presents with extensive herpetic vesicles on the penis.The physician performs surgical excision of the lesions and closes the incisions with sutures.

Documentation should include the type, size, and location of the lesion(s), the method of destruction used, anesthesia administered, and any complications encountered. Photographs may be helpful.

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