2025 CPT code 80414
(Active) Effective Date: N/A Revision Date: N/A Laboratory - Evocative/Suppression Testing Procedures Pathology and Laboratory Procedures Feed
Chorionic gonadotropin stimulation panel to measure testosterone response; includes two testosterone assays on three pooled blood samples.
Modifiers may apply depending on the specific circumstances. For example, modifier 90 (reference laboratory) may be appropriate if the testing is performed by an outside laboratory. Modifier 91 (repeat test) may apply if the test is repeated due to insufficient results. Modifiers are payer specific.
Medical necessity is established by the presence of symptoms suggestive of hypogonadism or delayed puberty, or as part of the ongoing management of a condition affecting testosterone production. The test helps differentiate between primary and secondary hypogonadism.
The laboratory analyst performs all technical aspects of the test, including the assays. The clinician is responsible for ordering the test, obtaining the patient's informed consent, collecting the blood samples (potentially using a separate procedure code), and interpreting the results within the context of the patient's clinical presentation.
- Pathology and Laboratory Procedures
- Pathology and Laboratory Procedures > Evocative/Suppression Testing Procedures
In simple words: This lab test checks how well your body makes testosterone after receiving a hormone injection. It involves taking three blood samples, combining them, and performing two separate tests to measure testosterone levels. This helps doctors understand if there are any problems with your testosterone production.
This CPT code, 80414, represents a chorionic gonadotropin (hCG) stimulation panel designed to assess testosterone response.The panel necessitates two separate testosterone assays (84403 x 2) performed on three pooled blood samples. This involves collecting three blood specimens, pooling them, and then conducting the two testosterone assays on this pooled sample. The procedure aims to evaluate testosterone production in response to hCG stimulation, providing insights into potential Leydig cell dysfunction or hypogonadism.
Example 1: A 35-year-old male presents with symptoms of hypogonadism, including decreased libido and erectile dysfunction.The clinician orders this panel to assess testosterone production in response to hCG stimulation to determine the etiology of his symptoms., A 17-year-old male is experiencing delayed puberty.This panel is used to evaluate his Leydig cell function and determine if there is a problem with testosterone production., A 40-year-old male with a history of testicular cancer undergoes post-treatment monitoring.This panel is part of the routine assessment to evaluate his endocrine function and identify any potential recurrence.
* Patient demographics and medical history.* Reason for ordering the test (clinical indication).* Documentation of hCG administration (dosage, time, route).* Timing of blood sample collection (baseline and post-stimulation).* Laboratory reports showing the two testosterone assays (84403 x 2) performed on three pooled blood samples.* Clinician's interpretation of the results.
** The three pooled blood samples should be collected at intervals to ensure accurate assessment of testosterone levels. Results should be interpreted in context with the patient's clinical presentation and other relevant diagnostic information.This panel is primarily utilized for male patients.Always refer to the most current CPT codebook and payer guidelines for the most up-to-date information on billing and coding.
- Revenue Code: T1H (LAB TESTS - OTHER (NON-MEDICARE FEE SCHEDULE))
- Payment Status: Active
- Modifier TC rule: Not applicable; this is a complete panel code.
- Specialties:Endocrinology, Urology
- Place of Service:Office, Hospital (outpatient), Laboratory