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2025 CPT code 80415

Chorionic gonadotropin stimulation panel; estradiol response. This panel includes two estradiol assays (82670) on three pooled blood samples.

This code represents the laboratory component only. Report the administration of the evocative agent separately.Each panel component must be included. Report separately any tests performed beyond what is listed as being included in the code’s description.

Modifiers may be applicable depending on the circumstances. For instance, modifier 59 may be used to indicate a distinct procedural service.

Medical necessity must be established for the use of this test. It should be justified by the patient's clinical condition and the need to assess ovarian function for diagnostic or treatment purposes.

A laboratory professional performs the technical aspects of the test, including the estradiol assays. Another healthcare provider may collect the blood samples.

IMPORTANT:If only the estradiol assay is performed without the stimulation test, use code 82670. For a chorionic gonadotropin stimulation test measuring testosterone response, use code 80414. Specimen collection may be reported separately using codes like 36415.

In simple words: This test measures how your body's estradiol levels respond to a hormone injection.It helps doctors understand how your ovaries are functioning.

This panel involves the administration of human chorionic gonadotropin (hCG) and the measurement of its effects on estradiol levels. The procedure involves collecting three blood samples at timed intervals, pooling them, and performing two separate estradiol assays (82670). The first assay establishes a baseline estradiol level, and the second measures the response after hCG administration.This test helps assess ovarian function and can be used to evaluate female reproductive health, including readiness for in vitro fertilization (IVF) or response to hormone replacement therapy.

Example 1: A woman undergoing infertility treatment needs to assess ovarian reserve and predict response to IVF medications., A physician suspects ovarian dysfunction in a patient experiencing irregular menstrual cycles and wants to evaluate estradiol response to hormonal stimulation., A patient on hormone replacement therapy requires monitoring of estradiol levels to ensure appropriate hormonal balance.

Documentation should include the reason for testing, the dates and times of blood sample collection, the dosage of hCG administered, and the results of both estradiol assays.Any relevant clinical findings related to the patient's reproductive health should also be noted.

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