2025 CPT code 82310

Assay of calcium; total.

When calcium is measured in multiple specimens from different sources or at different times, report 82310 separately for each. Do not report calculated values derived from other tests unless specifically ordered by the physician. If an additional analyte (e.g., urinary creatinine) is performed to adjust for variations in urine concentration, report both analyte codes.

Modifiers may be applicable. Modifier 91 is used for repeat laboratory tests. Modifier 59 may be used to indicate a distinct procedural service.

Medical necessity for 82310 is established when the test is ordered to evaluate signs, symptoms, or conditions related to calcium imbalances, such as hypercalcemia, hypocalcemia, or disorders affecting bone metabolism.The documentation should clearly support the clinical rationale for the test.

The laboratory professional performs the assay, typically using spectrophotometry or other validated methods, to determine the total calcium concentration in the provided serum specimen.

IMPORTANT Consider using codes 80048, 80050, 80053, or 80069 if calcium is part of a panel. For ionized calcium, use code 82330.

In simple words: This test measures the total amount of calcium in your blood. Calcium is important for healthy bones, muscles, nerves, and blood clotting.

This code represents the laboratory procedure for quantitatively measuring the total amount of calcium in a serum sample.It is used to assess calcium levels, which are essential for various bodily functions, including bone health, muscle function, nerve signaling, and blood clotting.

Example 1: A patient presents with symptoms of hyperparathyroidism, such as fatigue, muscle weakness, and kidney stones. The physician orders a calcium test (82310) to evaluate the patient's calcium levels., A patient with a history of malignancy is undergoing routine monitoring. The oncologist orders a calcium test (82310) to screen for hypercalcemia, a common complication of cancer., A patient with chronic kidney disease requires regular assessment of their electrolyte levels.A calcium test (82310) is included as part of their routine blood work.

The documentation should include the reason for the test, the date and time of specimen collection, and the source of the specimen (e.g., serum). Any relevant clinical findings or diagnoses should also be noted.

** Phosphorus levels are often tested concurrently with calcium, especially when previous results were abnormal.Providers sometimes abbreviate this test as "Ca".

  • Revenue Code: T1H
  • Payment Status: Active
** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.