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2025 CPT code 82330

Measures ionized calcium in serum, blood, or capillary samples.

Consult the current CPT coding guidelines for chemistry procedures. Pay attention to guidelines on reporting multiple specimens and calculated analytes.The guidelines may be updated periodically.

Modifiers may be applicable depending on the circumstances of service.Consult the official CPT manual for appropriate modifier use.

Medical necessity for 82330 is established based on clinical indications, such as the monitoring of critically ill patients, management of electrolyte imbalances, diagnosis and monitoring of conditions affecting calcium metabolism, or as part of a comprehensive metabolic panel in specific situations.The ordering physician must document the medical rationale for the test.

The clinical responsibility lies with the laboratory analyst who performs the quantitative measurement of ionized calcium using an ion-selective electrode method.Interpretation of results falls under the responsibility of the ordering physician.

IMPORTANT:Code 82310 (Calcium; total) can be billed together with 82330 if both tests are performed and clinically indicated. Code 80047 (Basic metabolic panel [Calcium, ionized]) includes ionized calcium testing.

In simple words: This lab test measures the active form of calcium in your blood. It's often used to monitor calcium levels during surgeries and in patients with kidney problems or other conditions affecting calcium balance.

This CPT code represents the quantitative measurement of ionized calcium, typically using an ion-selective electrode.The procedure involves measuring the physiologically active, free form of calcium in a serum, blood, or capillary sample. This test is crucial in various clinical situations, including the management of patients with chronic renal failure, multiple myeloma, acid-base imbalances, nephritic syndrome, and malabsorption.The results are expressed quantitatively.

Example 1: A patient undergoing major surgery requires frequent monitoring of ionized calcium levels due to the potential for hypocalcemia during the procedure.82330 is used for point-of-care testing to guide treatment decisions., A patient with chronic kidney disease presents with symptoms suggestive of hypocalcemia.82330 is ordered to assess the free calcium level and guide treatment with calcium supplements and/or vitamin D., A patient with suspected multiple myeloma requires evaluation of calcium homeostasis.Measurement of ionized calcium (82330) is essential to assess the severity of the disease and monitor treatment response.

* Physician's order specifying the test (ionized calcium).* Patient demographics and identifying information.* Date and time of sample collection.* Method used for ionized calcium measurement.* Quantitative results of the test.* Clinical information relevant to the indication for testing.

** Always ensure proper documentation supports the medical necessity for this test.The result interpretation should be done by a qualified healthcare professional. Point-of-care testing is common.

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