2025 CPT code 82960

Glucose-6-phosphate dehydrogenase (G6PD) screen; qualitative.

Follow CPT guidelines for laboratory and pathology coding, adhering to appropriate test selection and reporting rules.For multiple specimens or tests from different sources, report each separately.

Modifiers may be applicable depending on the specific circumstances of the testing.Refer to CPT guidelines for modifier usage.

Medical necessity for G6PD screening is established when there is clinical suspicion of G6PD deficiency based on patient history (e.g., unexplained hemolytic episodes, family history), ethnicity, exposure to potential triggers (medications, fava beans), and clinical presentation (e.g., jaundice, anemia).Newborn screening is based on state guidelines.

A laboratory analyst performs this test.The clinical responsibility includes collecting the blood sample, performing the qualitative G6PD assay, and reporting the results. A physician interprets the results in the context of patient history and clinical findings.

IMPORTANT For quantitative G6PD testing, use CPT code 82955.If a glucose tolerance test with medication is also performed, use CPT code 96374 in addition to this code.

In simple words: This blood test checks for a low level of an enzyme called G6PD.Having enough G6PD protects red blood cells from damage.A low level can lead to anemia. This test helps doctors determine if you need to avoid certain medicines.

This CPT code represents a qualitative screening test for Glucose-6-phosphate dehydrogenase (G6PD) deficiency.The test assesses the presence or absence of sufficient G6PD enzyme activity in red blood cells. It is a qualitative test, indicating deficiency or sufficiency, unlike a quantitative test which measures the exact enzyme level.The test is performed on a blood sample, typically using methods like fluorescent spot testing. This screening is valuable for identifying individuals at risk for hemolytic anemia, particularly those of certain ethnicities. The test aids in diagnosis and guides medication choices to avoid hemolytic reactions in patients with G6PD deficiency.

Example 1: A patient of Southeast Asian descent presents with symptoms suggestive of hemolytic anemia after consuming fava beans.The physician orders a G6PD screen (82960) to assess for G6PD deficiency as a potential cause., A patient requires a medication known to trigger hemolytic anemia in individuals with G6PD deficiency. Prior to prescribing the medication, the physician orders a G6PD screen (82960) to ensure patient safety., A newborn infant presents with jaundice.To investigate potential causes, including G6PD deficiency, the physician orders a G6PD screen (82960).

Patient demographics, reason for testing, date and time of specimen collection, specimen type (blood), test results (positive/negative), and physician interpretation of results in relation to the clinical picture are required documentation.

** The screening test (82960) is qualitative; a quantitative test (82955) provides a precise measurement of G6PD enzyme activity, which may be necessary in some circumstances.

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