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BETA v.3.0

2025 CPT code 84295

This test measures the concentration of sodium in serum, plasma, or whole blood.

When ordering tests for which Medicare or Medicaid reimbursement will be sought, physicians should only order tests that are medically necessary for the diagnosis or treatment of the patient.Do not use potassium oxalate/sodium fluoride anticoagulants. Indicate on the order slip and announce to lab personnel if the sample is a CODE; the sample will receive priority analysis. STAT/CODE samples should be whole blood.

Modifiers may be applicable to 84295.Modifier 59 (Distinct Procedural Service) is used to indicate that a procedure or service was distinct or independent from other services performed on the same day. Modifier 91 (Repeat Clinical Diagnostic Laboratory Test) is used when a laboratory test is repeated on the same day.Modifier 90 (Reference Outside Laboratory) can be used to report that the specimen was sent to a reference laboratory for analysis. Modifier CB is used for ESRD purposes to denote that the service is not part of the composite rate. Modifier CF indicates that AMCC tests are not part of the composite rate.

Medical necessity for a serum sodium test is determined by the patient's clinical condition and the physician's judgment.The test is typically medically necessary when there is a suspicion of an electrolyte imbalance, dehydration, fluid overload, or conditions affecting sodium regulation.

The lab analyst performs the technical lab steps to measure the concentration of sodium in serum, plasma, or whole blood.

In simple words: This test measures the level of sodium in your blood. Sodium is an important mineral that helps control the amount of water in your body.It's found in many foods, including table salt.

The lab analyst performs the technical lab steps to measure the concentration of sodium in serum, plasma, or whole blood to detect increased or decreased levels. Sodium is an ion obtained from diet, including table salt, that regulates water content in the body. The body very tightly regulates, or balances, sodium for many different essential organ and cellular functions. The test may use methods such as potentiometry, in which electrodes that are specific for sodium ions measure the amount of electrical activity, or potential, created by the sodium ions that are dissolved in a solution. Clinicians may order this test to evaluate patients for decreased sodium (hyponatremia), which may be the result of excess sodium loss from diuretics, diarrhea, vomiting, or Addison’s disease; it may also be due to excess fluid accumulation from edema or syndrome of inappropriate antidiuretic hormone (SIADH). They may also order this test to evaluate patients for increased sodium (hypernatremia), which may be the result of dehydration, Cushing’s syndrome, or diabetes insipidus.

Example 1: A patient presents with symptoms of dehydration, including excessive thirst and fatigue. The physician orders a serum sodium test (84295) to assess the patient's sodium levels and determine the severity of dehydration., A patient with congestive heart failure is experiencing fluid retention. The physician orders a serum sodium test (84295) to monitor the patient's sodium balance and adjust medication accordingly., A patient on diuretic therapy presents with muscle weakness and confusion. The physician orders a serum sodium test (84295) to rule out hyponatremia as a potential side effect of the medication.

Medical record documentation should include the reason for the sodium test, the patient's signs and symptoms, and any relevant medical history. The type of specimen (serum, plasma, or whole blood) should also be documented.

** This test is also a component of several panels, including 80047 (Basic metabolic panel with ionized calcium), 80048 (Basic metabolic panel with total calcium), 80050 (General health panel), 80051 (Electrolyte panel), 80053 (Comprehensive metabolic panel), and 80069 (Renal function panel). When performed as part of a panel, 84295 is not reported separately.

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