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BETA v.3.0

2025 CPT code 84403

This code reports the total testosterone measurement in a patient's serum.

Refer to the current CPT guidelines for detailed information on the use of code 84403.Always follow payer specific guidelines.

Modifiers may be applicable, including those related to the technical component, professional component, or multiple tests. Consult current CPT guidelines for appropriate modifier usage.

Medical necessity for a total testosterone test (84403) is established based on clinical symptoms or findings suggestive of hormonal imbalances (e.g., hypogonadism, infertility, menstrual irregularities, virilization) or for monitoring response to hormonal therapy.Payer-specific guidelines should be consulted.

The clinical responsibility lies with the laboratory analyst who performs the test, including specimen handling and analysis. The ordering physician is responsible for medical decision-making based on the results.

IMPORTANT:May be ordered with 84402 (Testosterone, free).Collection of the specimen may be billed separately using codes such as 36415 (Collection of venous blood by venipuncture).

In simple words: This lab test measures the total amount of testosterone in a blood sample. Testosterone is a hormone important for sexual development and other bodily functions.

CPT code 84403 represents the total serum testosterone test, a quantitative measurement of total testosterone, encompassing both free and protein-bound forms, in a patient's serum sample.The test utilizes methods such as chromatography to separate and analyze the testosterone concentration.This test is used in the assessment of various conditions affecting hormonal balance, including hypogonadism, infertility, and other endocrine disorders in both males and females.

Example 1: A male patient presents with symptoms of low libido and fatigue. The physician orders a total testosterone test (84403) to evaluate for hypogonadism., A female patient experiences irregular menstrual cycles and hirsutism.The physician orders a total testosterone test (84403) to assess for potential hormonal imbalances., A pediatrician orders a total testosterone test (84403) for a teenager who is experiencing delayed puberty to evaluate for potential hormonal deficiencies.

Patient demographics, test requisition specifying 84403, date and time of specimen collection, method of collection (e.g., venipuncture), test results, and interpretation by the ordering physician.

** This test measures total testosterone, including both free and bound testosterone. For a measurement of only free testosterone, use CPT code 84402.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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