Start New EnglishEspañol中文РусскийالعربيةTiếng ViệtFrançaisDeutsch한국어Tagalog Library Performance
BETA v.3.0

2025 CPT code 85999

Unlisted hematology and coagulation procedure.

Refer to the AMA CPT guidelines for coding unlisted procedures.Always use the most specific code possible. If unsure, contact your payer for clarification.

Modifiers may be applicable depending on the circumstances of the service provided. Consult the CPT manual for appropriate modifier usage.

Medical necessity must be established by the ordering physician, documenting the clinical indication for the unlisted procedure and its relevance to the patient's diagnosis or treatment plan. The payer may require additional documentation to support medical necessity.

The clinical responsibility lies with the laboratory personnel performing and interpreting the unlisted hematology or coagulation test. The ordering physician is responsible for medical necessity and appropriate test selection.

IMPORTANT:Refer to CPT codes 85002-85810, 82009-84830, 86015-86835, and 86850-86985 for specific hematology, coagulation, chemistry, immunology, and transfusion medicine procedures.If a more specific Category III code exists, it should be used instead of 85999.

In simple words: This code is used for blood tests and clotting factor tests when there isn't a specific code for the particular test done.The doctor's office needs to explain why this code was used and provide detailed information about the test performed.

This CPT code reports hematology and coagulation procedures not otherwise specified in the CPT codebook (codes 85002-85810) or within the Chemistry (82009-84830), Immunology (86015-86835), or Transfusion Medicine (86850-86985) sections.Use this code only when no other appropriate CPT code exists.Detailed documentation justifying the use of this unlisted code, along with a comparison to similar coded procedures, is required for reimbursement.

Example 1: A patient presents with unusual bleeding tendencies.The laboratory performs a specialized coagulation assay not covered by a specific CPT code, requiring the use of 85999.Detailed methodology and results are documented., A patient with a history of leukemia undergoes a rare flow cytometry analysis to detect a specific leukemic cell subtype not included in standard panels.Code 85999 is used. The laboratory report describes the specialized cell markers, methodology, and findings., During a bone marrow biopsy, an unusual cell population is detected.The laboratory performs advanced molecular analysis to characterize this population, needing code 85999. A detailed report explaining the molecular techniques, target genes, and results is provided.

Comprehensive laboratory reports detailing the procedure performed, methodology employed, materials used, results obtained, and interpretation.A cover letter explaining why this unlisted code was used is mandatory.

** Accurate and detailed documentation is paramount for successful reimbursement when using CPT code 85999.Pre-authorization may be required by certain payers. This code should be used judiciously, only when no other appropriate code exists.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

Discover what matters.

iFrame™ AI's knowledge is aligned with and limited to the materials uploaded by users and should not be interpreted as medical, legal, or any other form of advice by iFrame™.