Start New EnglishEspañol中文РусскийالعربيةTiếng ViệtFrançaisDeutsch한국어Tagalog Library Performance
BETA v.3.0

2025 CPT code 86328

Single-step immunoassay for SARS-CoV-2 antibodies (qualitative or semiquantitative).

Follow CPT guidelines for immunology procedures.This code is for single-step immunoassays; use 86769 for multi-step methods.

Modifiers may be applicable depending on the circumstances of service.Consult CPT guidelines and payer specific requirements for applicable modifiers (e.g., 90 for outside lab, 91 for repeat test).

Medical necessity is established when a physician orders this test based on a valid clinical indication, such as evaluating a patient for possible past or current infection, screening potential blood donors, or monitoring post-exposure.

The lab analyst is responsible for performing the test and interpreting the results. The ordering physician is responsible for the clinical interpretation and patient management based on the results.

IMPORTANT:For multi-step SARS-CoV-2 antibody tests, use CPT code 86769.For SARS-CoV-2 antigen detection, use CPT code 87426. For SARS-CoV-2 nucleic acid detection, use CPT code 87635.HCPCS codes U0001 and U0002 may apply for specific COVID-19 testing kits.

In simple words: This lab test checks a blood sample for antibodies against the COVID-19 virus.It uses a simple, one-step method to see if you have antibodies, which means your body has fought off the virus at some point.

This CPT code, 86328, reports a single-step immunoassay to qualitatively or semiquantitatively detect antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in a patient specimen.The method typically involves a reagent strip containing specific antigens that react with antibodies in the sample (e.g., whole blood or serum), producing a color change. This test may be used to evaluate past infection, identify potential plasma donors, or assess current infection status.

Example 1: A patient presents with symptoms suggestive of past COVID-19 infection. The physician orders this test to confirm prior exposure and assess immunity., A blood bank needs to screen potential donors for COVID-19 antibodies to identify suitable plasma donors for patients with severe COVID-19., A patient is being monitored for COVID-19 symptoms after exposure. This test is used to determine if an infection is developing.

Patient demographics, date of service, specimen type (e.g., serum, whole blood), test results, and the method used for the immunoassay.Physician's order for the test and clinical indication for testing should be documented.

** This code is specifically for SARS-CoV-2 antibody testing.Always verify payer-specific coding and reimbursement guidelines before billing.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

Discover what matters.

iFrame™ AI's knowledge is aligned with and limited to the materials uploaded by users and should not be interpreted as medical, legal, or any other form of advice by iFrame™.