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2025 CPT code 86329

Qualitative or semiquantitative immunodiffusion not otherwise specified.

Adhere to CPT guidelines and payer-specific coding instructions.Appropriate documentation is crucial for accurate coding and reimbursement.

Modifiers may be applicable depending on the circumstances of service, such as modifier 90 (Reference laboratory) or other modifiers as indicated by payer rules.

Medical necessity is determined by the physician's clinical judgment based on the patient's symptoms, history, and other diagnostic findings.The test should be medically necessary to aid in the diagnosis or management of a specific condition.

The clinical responsibility lies with the laboratory personnel who perform the immunodiffusion assay and interpret the results. The ordering physician is responsible for medical decision-making based on the test results.

IMPORTANT:Code 86331 (Gel Immunodiffusion, Qualitative, Antigen or Antibody) may be used for qualitative gel immunodiffusion.Specific immunoassays may have their own dedicated CPT codes.

In simple words: This lab test looks at a sample of your blood (or other fluid) to measure the levels of certain proteins called immunoglobulins, which are part of your body's immune system. The test uses a special technique to detect these proteins and determine their amounts, helping doctors understand your immune response.

This CPT code, 86329, represents qualitative or semiquantitative immunodiffusion assays not otherwise specified in other CPT codes.The procedure involves analyzing a patient sample (serum, urine, or cerebrospinal fluid) for the presence and concentration of immunoglobulins (antibodies) using an immunodiffusion method.The sample is placed in a gel containing antigens, and the resulting precipitation patterns are interpreted to determine the immunoglobulin levels.This test is used to evaluate various conditions, and its interpretation may aid in diagnosis of different diseases.

Example 1: A patient presents with symptoms suggestive of a fungal infection. The physician orders code 86329 to assess immunoglobulin levels and aid in the diagnosis of blastomycosis., A patient with a history of autoimmune disease undergoes routine immunoglobulin level monitoring.Code 86329 is used to quantitatively assess immunoglobulin levels in serum., A patient presents with suspected staphylococcal infection. The physician orders code 86329 to evaluate teichoic acid antibody levels.

Physician order specifying the test, patient demographics, date and time of specimen collection, type of specimen (serum, urine, cerebrospinal fluid), and results of the immunodiffusion assay.Relevant clinical information supporting medical necessity should also be documented.

** This code is for immunodiffusion tests not otherwise specified by other more specific codes. Ensure that the test performed does not fall under any other more specific CPT code.Always refer to the most current CPT codebook and payer guidelines for accurate coding.

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