2025 CPT code 86832
(Active) Effective Date: N/A Revision Date: N/A Pathology and Laboratory Procedures - Tissue Typing Immunological Procedures Immunology Procedures Feed
Identifies specific antibodies to HLA Class I antigens in patient serum using a high-definition solid-phase immunoassay.
Modifiers may apply depending on the circumstances of service, place of service, and other factors. Consult CPT guidelines and payer-specific instructions for modifier usage.Modifier -90 (Reference laboratory) may be applicable if testing is done at an outside laboratory.
Medical necessity is established when the ordering physician has a clinical indication for assessing the presence of specific HLA Class I antibodies in the context of organ or bone marrow transplantation to evaluate compatibility and prevent or manage rejection.
The clinical responsibility lies with the laboratory analyst who performs the technical steps of the assay, interprets the results, and reports the specific HLA Class I antibodies detected in the patient's serum.The ordering physician is responsible for ordering the test based on clinical indication and interpreting the results within the context of patient care.
In simple words: This lab test checks your blood for specific antibodies that might attack a donor organ or bone marrow in a transplant. It uses a special method to precisely identify which antibodies are present, helping doctors find the best match for a successful transplant.
This CPT code (86832) represents a high-definition qualitative panel for identifying antibody specificities to HLA Class I antigens.The procedure uses a solid-phase immunoassay, such as microspheres, beads, ELISA, or flow cytometry, with a methodology enabling the testing of individual antigens per bead. The lab analyst mixes the patient serum with the antigen-coated beads and a marker (e.g., fluorescent immunoglobulin) to detect antibody-antigen reactions. The results pinpoint the specific HLA Class I antibodies present in the serum.
Example 1: A patient is awaiting a kidney transplant.Pre-transplant testing reveals a good HLA match with a potential donor, but antibody screening shows high levels of HLA Class I antibodies.Code 86832 is used to perform high-resolution identification of specific HLA Class I antibody specificities to assess the risk of rejection and guide transplantation decisions., A patient has received a kidney transplant and is experiencing signs of rejection.Code 86832 is used to monitor the development of new donor-specific HLA Class I antibodies to guide treatment interventions and assess the transplant's long-term prognosis., A patient is undergoing pre-transplant evaluation for a bone marrow transplant.The test (86832) will identify the specific Class I antibodies in the patient's serum that could cause rejection of the donor marrow, allowing for a more informed assessment of transplant feasibility and helping the medical team find the most compatible donor.
** This code is for high-resolution HLA Class I antibody identification.It is distinct from lower-resolution or semi-quantitative tests.If interfering antibodies are present, and removal is necessary before retesting, the code should be reported separately for each test performed.Payers may have specific requirements and policies regarding reimbursement for this test; it's important to confirm the payer's specific policy and guidelines before billing.
- Revenue Code: T1H (LAB TESTS - OTHER (NON-MEDICARE FEE SCHEDULE))
- RVU: Information not available in provided text.Consult AMA CPT guidelines or payer-specific fee schedules for RVU data.
- Global Days: Not applicable.
- Payment Status: Active
- Modifier TC rule: Not applicable. This is a professional service provided by the laboratory.
- Fee Schedule: Fee schedule data is not included in provided sources; this information varies by payer and geographic location.Consult payer-specific fee schedules or professional fee references for this information.
- Specialties:Transplantation surgery, immunology, pathology, hematology
- Place of Service:Hospital (Inpatient or Outpatient), Reference Laboratory, Independent Lab