2025 CPT code 87482

Infectious agent detection by nucleic acid (DNA or RNA); Candida species, quantification

For multiple specimens/sites use modifier 59. For repeat laboratory tests performed on the same day, use modifier 91. Do not report molecular diagnostic codes (e.g., 81161, 81200-81408) in combination with or instead of 87140-87158 if molecular probes, nucleic acid sequencing, chromatography or immunological techniques are used.

Modifiers 59 (Distinct Procedural Service) and 91 (Repeat Clinical Diagnostic Laboratory Test) may be applicable. Refer to the provided modifier list for other potential modifiers.

Medical necessity is established by the presence of signs, symptoms, or conditions that suggest a Candida infection, or the need to monitor an existing infection.

The lab analyst processes the specimen, performs amplification techniques (e.g., PCR), and uses a labeled nucleic acid probe to visualize and quantify the Candida species.

IMPORTANT For Candida antibody tests or skin tests, use 86628 or 86485. For direct probe or amplified probe tests for Candida, use 87480 or 87481.

In simple words: This lab test measures the amount of Candida (a type of yeast) in a sample.It uses a special DNA/RNA probe to detect and count the Candida, helping doctors diagnose and monitor infections like vaginal yeast infections or thrush.

This test quantifies Candida species infection using nucleic acid probe technique. The lab analyst processes a direct specimen (e.g., vaginal swab, sputum) and amplifies specific nucleic acid sequences (e.g., via PCR).A labeled nucleic acid probe hybridizes with the amplified sequences, allowing visualization and quantification of the target organism.

Example 1: A patient presents with symptoms of a vaginal yeast infection. A vaginal swab is collected and tested using code 87482 to confirm and quantify the Candida infection., A patient with a weakened immune system develops white patches in their mouth. A throat swab is taken and analyzed using 87482 to diagnose and quantify oral thrush (Candida infection)., A patient undergoing treatment for a systemic Candida infection has repeat testing using 87482 to monitor the effectiveness of the therapy.

Documentation should include the specimen source, the reason for testing, and relevant clinical findings.

  • Revenue Code: T1H
  • Specialties:Microbiology, Infectious Disease, Gynecology (for vaginal infections), Otolaryngology (for oral thrush)
  • Place of Service:Independent Laboratory, Hospital Laboratory, Physician's Office
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