2025 CPT code 87527

Quantification of hepatitis G virus using nucleic acid probe techniques.

Adhere to CPT coding guidelines for microbiology procedures and nucleic acid testing. Pay close attention to distinguishing this code from related tests such as 87525 and 87526.

Modifiers such as 59 (distinct procedural service) and 91 (repeat test) may be applicable under certain circumstances. Refer to the CPT manual for specific usage criteria.

Medical necessity for this test is established when the physician has a clinical indication to assess the presence and quantity of HGV infection in a patient, such as evaluating symptoms of hepatitis, investigating liver abnormalities, or assessing post-transfusion risk.The specific payer's guidelines should be reviewed to ensure compliance.

The clinical responsibility lies with the laboratory analyst who performs the test and interprets the results.The ordering physician is responsible for utilizing the results in the context of the patient's overall clinical picture and deciding on appropriate treatment.

IMPORTANT Distinguish from 87525 (qualitative direct probe) and 87526 (qualitative amplified probe).

In simple words: This lab test measures the amount of hepatitis G virus in a blood sample.It uses special techniques to make many copies of the virus's genetic material and then counts them to determine the level of infection.

This CPT code represents the quantification of hepatitis G virus (HGV) in a clinical specimen using nucleic acid probe technology.The procedure involves processing a specimen (typically serum or plasma), amplifying the target nucleic acid sequence (e.g., using PCR), and then quantifying the amplified sequences using a labeled nucleic acid probe via hybridization. The result provides a numerical representation of the viral load.

Example 1: A patient presents with symptoms suggestive of hepatitis, and the physician orders this test to quantify the level of HGV infection to assess the severity of the disease and guide treatment decisions., A patient undergoing evaluation for liver disease has this test performed to determine the presence and quantity of HGV, especially if they have co-infections with other hepatitis viruses (like HBV or HCV) or HIV., A patient who received a blood transfusion experiences abnormal liver function tests, prompting the physician to order this test to assess for potential HGV infection acquired through the transfusion.

** Always refer to the most current CPT codebook and payer-specific guidelines for accurate coding and reimbursement.This information is for educational purposes only and does not constitute medical advice.

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