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2025 CPT code 87633

Detects multiple respiratory viruses (12-25 targets) using multiplex reverse transcription and amplified probe techniques.

Refer to CPT guidelines for microbiology procedures and the specific coding guidelines of the payer.

Modifiers 59 (distinct procedural service) and 91 (repeat test on the same day) may apply under specific circumstances.

Medical necessity for 87633 is established when a physician orders the test based on a patient's clinical presentation (e.g., respiratory symptoms) to diagnose a suspected respiratory viral infection and guide appropriate treatment.The test's purpose is to differentiate among various respiratory viruses, enabling targeted therapy and infection control measures.

The clinical responsibility lies with the laboratory analyst who performs the specimen processing, amplification (e.g., PCR), hybridization, and analysis to identify the respiratory viruses.

IMPORTANT:Use 87632 for 6-11 respiratory virus targets.For influenza virus typing/subtyping only, see 87501-87503. For assays including influenza and other respiratory viruses, use 87631-87633. For detection of multiple infectious agents (single result), use 87800, 87801.

In simple words: This lab test identifies 12 to 25 different types of respiratory viruses from a sample (like blood). It uses special techniques to make many copies of the virus's genetic material and then finds which virus is present.

This CPT code, 87633, encompasses the detection of multiple respiratory viruses (12-25 targets) using a combination of multiplex reverse transcription and amplified probe techniques.The procedure involves amplification of nucleic acid sequences followed by detection using labeled probes.The results identify the specific virus or subtypes present in the sample.

Example 1: A patient presents with flu-like symptoms.The physician orders 87633 to identify the specific respiratory virus causing the illness, guiding treatment decisions., A child is hospitalized with severe respiratory distress.87633 helps determine the causative agent (e.g., RSV, influenza) to direct appropriate care., An outbreak of respiratory illness occurs in a nursing home.87633 aids in identifying the prevalent virus, aiding in infection control measures and treatment strategies.

* Patient demographics and medical record number.* Physician's order specifying the test.* Specimen collection date and time, along with the method of collection and the source of the sample (e.g., nasal swab, sputum).* Detailed report from the laboratory including the methods used, the specific viruses tested for, and the results obtained.

** This code is appropriate for use in various healthcare settings, including physician offices, hospitals, and independent clinical laboratories.Accurate reporting requires clear documentation of the specific viruses tested for and the results obtained. The number of target viruses (12-25) is crucial for selecting this code versus 87632.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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