2025 CPT code 87661

Detects Trichomonas vaginalis using nucleic acid amplified probe technique.

Follow CPT guidelines for microbiology procedures and infectious agent antigen detection. Modifier 59 should be used for multiple specimens/sites. Modifier 91 should be used for repeat tests on the same day.

Modifiers 59 and 91 are applicable as described in the CPT guidelines.

Medical necessity for code 87661 is established based on the presence of symptoms or risk factors suggestive of trichomoniasis (e.g., vaginal discharge, dysuria, dyspareunia), or as part of routine STI screening in high-risk populations (e.g., pregnant women).

The clinical responsibility lies with the laboratory analyst who performs all technical steps, including specimen analysis, nucleic acid amplification (e.g., PCR), probe hybridization, and interpretation of results. The ordering physician is responsible for clinical decision-making based on the test results and patient history.

IMPORTANT For direct probe technique, use 87660. For direct optical observation, use 87808. If multiple organisms are tested using amplified probe technique, use 87801.

In simple words: This lab test checks for Trichomonas vaginalis, a parasite that causes a sexually transmitted infection.The test uses a special technique to quickly and accurately detect the parasite's genetic material in a sample.

This CPT code encompasses the laboratory analysis for the detection of Trichomonas vaginalis using a nucleic acid amplified probe technique.The procedure involves the amplification of specific DNA or RNA sequences of T. vaginalis from a specimen (commonly a urogenital swab) followed by detection using a labeled nucleic acid probe through hybridization. The amplified probe technique enhances the sensitivity and speed of detection compared to traditional culture methods.

Example 1: A female patient presents with vaginal discharge and symptoms suggestive of trichomoniasis.A vaginal swab is collected and sent for testing using code 87661. The results are positive for T. vaginalis, confirming the diagnosis and guiding treatment., A male patient with penile discharge undergoes testing for STIs. Code 87661 is used for the analysis of a penile swab; the result is negative for T. vaginalis., As part of a routine STI screening during a prenatal visit, a pregnant woman undergoes a vaginal swab test using code 87661.The results are negative, reassuring the patient and healthcare providers.

* Patient demographics and relevant medical history.* Specimen collection details (date, time, source, and collection method).* Complete and accurate laboratory report including the methodology used and specific results.* Physician's order indicating the reason for the test and clinical suspicion.

** The test result should be interpreted in conjunction with the patient’s clinical presentation and other diagnostic findings.

  • Revenue Code: T1H (LAB TESTS - OTHER)
  • Payment Status: Active
  • Modifier TC rule: Not applicable.
  • Specialties:Obstetrics and Gynecology, Infectious Disease, Urology, Family Medicine
  • Place of Service:Office, Hospital, Laboratory, Outpatient Center
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