In simple words: This test helps doctors understand certain characteristics of tumors by analyzing how they react to special stains. A computer helps count the stained cells, and a doctor then uses this information to make a diagnosis and guide treatment decisions.

This code represents a quantitative or semiquantitative immunohistochemistry (IHC) analysis of a tumor specimen using computer-assisted technology.A single antibody stain is applied to the specimen, and the computer assists in quantifying or semi-quantifying the stained cells. The pathologist then interprets the results to provide a diagnosis. This procedure is often used for biomarkers such as Her-2/neu, estrogen receptor, and progesterone receptor.

Example 1: A patient with suspected breast cancer has a biopsy performed. The specimen is sent for IHC staining for estrogen receptor and progesterone receptor, using computer-assisted technology to quantify the stained cells. 88361 is reported., A patient with a melanoma undergoes surgery. The tumor specimen is tested for Her-2/neu expression using a computer-assisted IHC analysis to guide treatment. 88361 is reported., A patient has a biopsy of a suspicious skin lesion. The specimen is stained with a single antibody and analyzed with computer assistance to determine the percentage of stained cells for diagnostic purposes. 88361 is reported.

Documentation should include the type of specimen, the antibody used, the results of the analysis (quantitative or semiquantitative), and the pathologist's interpretation and diagnosis.