2025 CPT code 90384

Rho(D) immune globulin (RhIg), human, full-dose, for intramuscular use.

Always refer to the latest CPT guidelines for accurate coding.The code should be used only with appropriate administration codes and cannot be used with modifier 51.

Modifiers may apply based on the circumstances of service. Refer to the most current CPT and payer guidelines.

Medical necessity for Rho(D) immune globulin is typically established by the patient's Rh-negative blood type and the potential for exposure to Rh-positive blood or cells. This is commonly seen in pregnant women who are Rh-negative and have an Rh-positive baby, or in individuals receiving blood transfusions.

The physician or qualified healthcare professional is responsible for assessing the patient's need for Rho(D) immune globulin, administering the intramuscular injection, and documenting the procedure appropriately.This may include reviewing the patient's medical history, evaluating the potential for Rh incompatibility, selecting the appropriate dose of Rho(D) immune globulin, and ensuring proper injection technique.Post-injection monitoring for any adverse reactions may also be included in the clinical responsibility.

IMPORTANT J2790 (HCPCS code) may be used as an alternative, depending on payer preferences.Additional administration codes (96365-96375) are required for complete billing.

In simple words: This code is for a shot of Rhogam, a medicine that prevents problems related to Rh incompatibility during pregnancy or after a blood transfusion.This code only covers the cost of the medicine itself; a separate code is needed to bill for the actual injection.

CPT code 90384 represents the administration of a full dose of human Rho(D) immune globulin for intramuscular injection.This code specifically designates the product itself and does not encompass the administration procedure.Rho(D) immune globulin is used to prevent Rh incompatibility issues in pregnancy and other clinical scenarios where Rh sensitization is a concern. The injection prevents the formation of antibodies against the Rh factor, thereby mitigating potential complications. This code should be used in conjunction with an appropriate administration code, such as those within the 96365-96375 series, to reflect the complete service.Modifier 51 should not be appended if another procedure is performed concurrently.

Example 1: A pregnant woman with Rh-negative blood receives Rho(D) immune globulin at 28 weeks gestation to prevent Rh sensitization of the fetus., An Rh-negative patient receives a transfusion of Rh-positive blood and is subsequently given Rho(D) immune globulin to prevent the development of anti-Rh antibodies., A patient with autoimmune thrombocytopenic purpura (ITP) and Rh-positive blood receives Rho(D) immune globulin as part of their treatment plan.

Patient demographics, medical history (especially related to pregnancy or blood transfusions), Rh factor status, date and time of injection, dose administered, injection site, and any observed reactions or complications.

** Always confirm payer-specific coding and reimbursement guidelines.This code is for the product only; administration is billed separately.This code should not be reported with modifier 51.

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