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2025 CPT code 90476

Adenovirus vaccine, type 4, live, for oral use.

Codes 90476-90759 must be used with an immunization administration code (90460, 90461, 90471, 90472, 90473, 90474) for non-SARS-CoV-2 vaccines.Do not code components of combination vaccines separately. If no specific code exists, use an unlisted procedure code.

Modifier 51 should not be used with code 90476 when reported with administration codes 90460-90474 or 90480.

Medical necessity is established based on the patient's risk factors, such as age, immune status, and exposure to adenovirus.Prophylactic use for high-risk individuals is generally considered medically necessary. The CDC immunization schedule can help determine necessity in children.

The provider administers a single oral dose of the adenovirus type 4 vaccine.

IMPORTANT:If a specific vaccine code is not available, use the unlisted procedure code.Code 90477 is used for Adenovirus vaccine, type 7, live, for oral use.

In simple words: This code is for giving a type of virus vaccine (adenovirus type 4) by mouth to help prevent adenovirus infections.It's a live vaccine, meaning it contains a weakened form of the virus.

This CPT code, 90476, represents the administration of an adenovirus vaccine, type 4, which is live and intended for oral use.The vaccine is harvested from human diploid tissue and administered to elicit immunity against adenovirus infection.This code should be used in conjunction with an immunization administration code (90460, 90461, 90471, 90472, 90473, 90474) unless administered with a SARS-CoV-2 vaccine at the same encounter.

Example 1: A 2-year-old child receives the oral adenovirus type 4 vaccine as part of their routine immunization schedule during a well-child visit., An immunocompromised adult receives the vaccine prophylactically before travelling to an area with high adenovirus infection rates., A patient with a history of adenovirus infections receives the vaccine to reduce their risk of future infections during a routine doctor's visit.

Patient's demographics, date of administration, vaccine lot number, and any adverse reactions should be documented.The administration code should also be documented.

** The vaccine abbreviations used in CPT codes reflect the latest ACIP recommendations at the time of publication.Interim updates will be made via the AMA CPT website.

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